AI-enabled Assessment of Cardiac Systolic and Diastolic Function from Echocardiography [PDF]
MICCAI ASMUS 2020, 2022 Left ventricular (LV) function is an important factor in terms of patient management, outcome, and long-term survival of patients with heart disease. The most recently published clinical guidelines for heart failure recognise that over reliance on only one measure of cardiac function (LV ejection fraction) as a diagnostic and treatment stratification ...
arxiv
Journal of Advanced Research, 2023 Introduction: Extracellular vesicles (EVs)-mediated cell-to-cell communication is crucial for hypoxia-induced cell proliferation and tissue repair, but its function in endogenous cardiac regeneration is still unknown.
Guoquan Wei +15 more
doaj
Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik +5 more
wiley +1 more source
A Multi-Trait Approach Identified Genetic Variants Including a Rare Mutation in RGS3 with Impact on Abnormalities of Cardiac Structure/Function [PDF]
arXiv, 2018 Heart failure is a major cause for premature death. Given heterogeneity of the heart failure syndrome, identifying genetic determinants of cardiac function and structure may provide greater insights into heart failure. Despite progress in understanding the genetic basis of heart failure through genome wide association studies, heritability of heart ...
arxiv
Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects. [PDF]
, 2019 Organogenesis involves integration of diverse cell types; dysregulation of cell-type-specific gene networks results in birth defects, which affect 5% of live births.
de Soysa, T Yvanka +9 more
core
The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila [PDF]
, 2018 Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure.
Hartley, Paul S. +3 more
core +1 more source
Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan +6 more
wiley +1 more source
Machine Learning Based on Natural Language Processing to Detect Cardiac Failure in Clinical Narratives [PDF]
arXiv, 2021 The purpose of the study presented herein is to develop a machine learning algorithm based on natural language processing that automatically detects whether a patient has a cardiac failure or a healthy condition by using physician notes in Research Data Warehouse at CHU Sainte Justine Hospital.
arxiv
The effectiveness of the cardiac resynchronization in a patient with ischemic cardiomyopathy [PDF]
, 2018 Cardiac resynchronization therapy (CRT) in multiple and large trials has been demonstrated to improve symptoms and decrease hospitalization and mortality of patients when used in addition to optimal medical therapy.
Bătăiosu, Constantin +5 more
core +4 more sources