Results 111 to 120 of about 1,199,408 (314)

Structural and Biochemical Kinetics of Cardiac Myosin and its Perturbation by a Known Heart Failure Drug Investigated with Transient Time-Resolved FRET [PDF]

, 2016
John A. Rohde, David D. Thomas, Joseph M. Muretta   +2 more
openalex   +1 more source

Progression of aerobic and anaerobic thresholds in cardiac rehabilitation: heart failure vs coronary artery disease [PDF]

, 2022
Pedro Custódio, Ana Rita Santos, L Moreno, Miguel Mendes   +3 more
openalex   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Implementation of a High-Sensitivity Troponin Assay and Its Association With Resource Utilization in Patients With Suspected Acute Coronary Syndrome

Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Objective: To examine the association between the implementation of high-sensitivity cardiac troponin (hs-cTn) and downstream resource utilization in patients presenting to the emergency department (ED) with suspected acute coronary syndrome (ACS ...
Radhika K. Neicheril, MD, Yosef Manla, MD, Daniel Chacon, MD, Kaylee Sarna, MSc, Alice Sonnino, MD, Jared Piotrkowski, MD, Kevin Perry, MD, David Snipelisky, MD   +7 more
doaj   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Sympathetic hyperinnervation drives abdominal aortic aneurysm development by promoting vascular smooth muscle cell phenotypic switching

Journal of Advanced Research
Introduction: Sympathetic hyperinnervation plays an important role in modulating the vascular smooth muscle cell (VSMC) phenotype and vascular diseases, but its role in abdominal aortic aneurysm (AAA) is still unknown.
Zhenquan Tang, Jingfang Xie, Ming Jin, Guoquan Wei, Ziwei Fu, Xiajing Luo, Chuling Li, Xiaoqian Jia, Hao Zheng, Lintao Zhong, Xinzhong Li, Junfen Wang, Guojun Chen, Yanmei Chen, Wangjun Liao, Yulin Liao, Jianping Bin, Senlin Huang   +17 more
doaj   +1 more source

Aggravated myocardial infarction-induced cardiac remodeling and heart failure in histamine-deficient mice [PDF]

, 2017
Jinmiao Chen, Tao Hong, Suling Ding, Long Deng, Mieradilijiang Abudupataer, Weiwei Zhang, Minghong Tong, Jianguo Jia, Hui Gong, Yunzeng Zou, Timothy C. Wang, Junbo Ge, Xiangdong Yang   +12 more
openalex   +1 more source

Programmable Compliance in Small‐Diameter Vascular Grafts by Design of Melt‐Electrowritten Scaffold Architectures for In Situ Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller, Christina Ahrens, Linda Grefen, Salma Mansi, Dario Arcuti, Elena De‐Juan‐Pardo, Felix Kur, Christian Hagl, Petra Mela   +8 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Extracellular‐Matrix‐Based Materials from Decellularized Tissue: Opportunities, Challenges, and Future Directions in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Extracellular matrix‐based materials derived from decellularized tissue (dECM) harness the tissue's native bioactivity to guide repair and regeneration across diverse clinical applications. This perspective highlights clinical uses of dECM biomaterials and advances in fabrication methods such as electrospinning and 3D printing.
Madeline Laude, Vasiliki Kolliopoulos, Antonios G. Mikos, Lisa J. White, Elizabeth Cosgriff‐Hernandez   +4 more
wiley   +1 more source