Results 111 to 120 of about 4,737,690 (404)
Advanced Healthcare Materials, EarlyView.AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan +3 more
wiley +1 more source
European Heart Journal, 2016 Left ventricular ejection fraction (LVEF) has been the central parameter used for diagnosis and management in patients with heart failure. A good predictor of adverse outcomes in heart failure when below ∼45%, LVEF is less useful as a marker of risk as ...
M. Čikeš, S. Solomon
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis +5 more
wiley +1 more source
Metabolic Modulation of Cardiac Metabolism in Heart Failure.
Cardiac failure review, 2018 Heart failure (HF) is associated with metabolic changes that cause a progressive impairment of cardiac and skeletal muscle high-energy phosphate production. As a consequence of the impaired cardiac metabolism, other processes are activated in the failing
G. Rosano, C. Vitale
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Plasma oxidation following polydopamine deposition can significantly reduce the surface hydrophobicity of polyurethane‐siloxanes without impacting surface roughness, thereby increasing fibroblast viability, adhesion, and extracellular matrix production and secretion.
Sophie Armstrong +5 more
wiley +1 more source
Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy. [PDF]
, 2019 Increased adrenergic tone resulting from cardiovascular stress leads to development of heart failure, in part, through chronic stimulation of β1 adrenergic receptors (βARs) on cardiac myocytes.
Irannejad, Roshanak +3 more
core +1 more source
Plasma N-Terminal Pro-Brain Natriuretic Peptide as Prognostic Marker in Fatal Cardial Decompensation with Sunitinib Malate Therapy [PDF]
, 2010 A 74-year-old man with metastatic renal cell carcinoma and a history of cardiac failure was treated with sunitinib malate. MUGA echocardiography could not detect a relevant change in the ejection fraction although the clinical situation of the patient ...
Haseke, Nicolas +4 more
core +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
Advanced Healthcare Materials, EarlyView.This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Monaldi Archives for Chest Disease, 2016 Cardiopulmonary exercise testing (CPET) is a non-invasive tool that provides the physician with relevant information to assess the integrated response to exercise involving pulmonary, cardiovascular, haematopoietic, neuro-psychological, and skeletal ...
Ugo Corrà, Massimo F. Piepoli
doaj +1 more source
Vagal nerve stimulation therapy: what is being stimulated? [PDF]
, 2014 Vagal nerve stimulation in cardiac therapy involves delivering electrical current to the vagal sympathetic complex in patients experiencing heart failure. The therapy has shown promise but the mechanisms by which any benefit accrues is not understood. In
Ardell, Jeffrey L +3 more
core +3 more sources