Results 171 to 180 of about 1,200,882 (301)

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

Case Report: Kearns Sayre Syndrome Complicated With Postpartum Cardiac Failure. [PDF]

open access: yesFront Med (Lausanne), 2022
Han C   +5 more
europepmc   +1 more source

Impact of Echocardiographic Cardiac Damage Staging on Mortality and Heart Failure Hospitalizations in Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement [PDF]

open access: gold
José Antonio Parada Barcía   +6 more
openalex   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

Acute Lymphoblastic Leukemia Presenting with Acute Decompensated Cardiac Failure.

open access: yesHeart Views, 2023
Abdelghani MS   +4 more
europepmc   +1 more source

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