Results 11 to 20 of about 1,199,408 (314)

Myocardial recovery evaluation from ventricular assist device in patients with dilated cardiomyopathy

open access: yesESC Heart Failure, 2022
Aims The removal of left ventricular assist device (LVAD) after myocardial recovery can provide survival benefits with freedom from LVAD‐associated complications.
Takayuki Gyoten   +6 more
doaj   +1 more source

Cardiac safety of tiotropium in patients with cardiac events: a retrospective analysis of the UPLIFT® trial. [PDF]

open access: yes, 2015
BackgroundTiotropium is an anticholinergic bronchodilator for symptom relief and reducing exacerbations with an established safety profile in patients with chronic obstructive pulmonary disease (COPD).
Decramer, Marc   +3 more
core   +1 more source

The relation between cardiac 123I-mIBG scintigraphy and functional response 1 year after CRT implantation [PDF]

open access: yes, 2020
Cardiac resynchronization therapy (CRT) is a disease-modifying therapy in patients with chronic heart failure (CHF). Current guidelines ascribe CRT eligibility on three parameters only: left ventricular ejection fraction (LVEF), QRS duration, and New ...
de Groot, J R   +7 more
core   +1 more source

COPD and cardiovascular disease [PDF]

open access: yes, 2019
COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020.
André, S.   +5 more
core   +3 more sources

Myocardial fibrosis in stroke survivors [PDF]

open access: yes, 2015
Stroke survivors are most likely to die of cardiac death, yet few undergo comprehensive cardiac assessment to look for reversible causes. Myocardial fibrosis (MF) is not only the hallmark of cardiomyopathy, but also a substrate for sudden cardiac death ...
Allgar, V.   +6 more
core   +1 more source

Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway

open access: yesJournal of Advanced Research, 2023
Introduction: Extracellular vesicles (EVs)-mediated cell-to-cell communication is crucial for hypoxia-induced cell proliferation and tissue repair, but its function in endogenous cardiac regeneration is still unknown.
Guoquan Wei   +15 more
doaj   +1 more source

LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization

open access: yesRedox Biology, 2022
Aims: Metabolic switching during heart development contributes to postnatal cardiomyocyte (CM) cell cycle exit and loss of regenerative capacity in the mammalian heart. Metabolic control has potential for developing effective CM proliferation strategies.
Yijin Chen   +17 more
doaj   +1 more source

A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function

open access: yesJACC: Basic to Translational Science, 2016
Myocardial infarction (MI) remains a dreadful disease around the world, causing irreversible sequelae that shorten life expectancy and reduce quality of life despite current treatment.
Isaac Perea-Gil, MS   +10 more
doaj   +1 more source

Cardiac cellular diversity and functionality in cardiac repair by single-cell transcriptomics

open access: yesFrontiers in Cardiovascular Medicine, 2023
Cardiac repair after myocardial infarction (MI) is orchestrated by multiple intrinsic mechanisms in the heart. Identifying cardiac cell heterogeneity and its effect on processes that mediate the ischemic myocardium repair may be key to developing novel ...
Wei Chen   +10 more
doaj   +1 more source

Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach

open access: yesnpj Systems Biology and Applications, 2017
Cardiology: Heart Failure Medication Reduces Heart Size The new wonder drug in heart failure management, Sacubitril/Valsartan, rejuvenates the heart by preventing its dilation. Using data from myocardial infarction and heart failure samples, we generated
Oriol Iborra-Egea   +6 more
doaj   +1 more source

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