Results 201 to 210 of about 1,050,190 (380)

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

open access: yesAdvanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran   +7 more
wiley   +1 more source

A Case Report of Cardiac Failure in a Patient on Teduglutide for High-Output Ileostomy Stoma. [PDF]

open access: yesCureus, 2023
Nair A   +5 more
europepmc   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

open access: yesAdvanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang   +12 more
wiley   +1 more source

Tuberous xanthoma with cardiac failure in a child. [PDF]

open access: yesJ Family Med Prim Care, 2022
Narasimhan M   +3 more
europepmc   +1 more source

Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics

open access: yesAdvanced Science, EarlyView.
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch   +4 more
wiley   +1 more source

Direct Link Between Cardiac Failure and Global Cerebral Atrophy in a Young Adult: A Case Report on Reduced Cerebral Artery Blood Flow. [PDF]

open access: yesAm J Case Rep, 2023
Sekiguchi H   +9 more
europepmc   +1 more source

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