Results 211 to 220 of about 1,050,190 (380)

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du   +9 more
wiley   +1 more source

The prognostic value of clinical frailty scale and outcomes in older patients undergoing left ventricular assist device implantation

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022
The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo   +3 more
wiley   +1 more source

Lung Metastases to the Heart with Atypical Clinical Manifestations of Cardiac Failure. [PDF]

open access: yesMedeni Med J, 2023
Hyriavenko N   +5 more
europepmc   +1 more source

Sympathetic hyperinnervation drives abdominal aortic aneurysm development by promoting vascular smooth muscle cell phenotypic switching

open access: yesJournal of Advanced Research
Introduction: Sympathetic hyperinnervation plays an important role in modulating the vascular smooth muscle cell (VSMC) phenotype and vascular diseases, but its role in abdominal aortic aneurysm (AAA) is still unknown.
Zhenquan Tang   +17 more
doaj  

P21‐Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy

open access: yesAdvanced Science, EarlyView.
Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li   +21 more
wiley   +1 more source

Improving osteoporosis treatment rates in inpatients admitted with hip fracture: A healthcare improvement initiative in a tertiary referral hospital

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 264-271, December 2022., 2022
Our hospital introduced a standardized protocol for the treatment of osteoporosis in patients admitted for hip fracture. The aim of this article was to describe its implementation as well as assess the protocol's effect on treatment rates and safety. In our analysis, there was significant improvement in treatment rates with no instances of acute kidney
Andrew Gan Lin   +5 more
wiley   +1 more source

Chronic anemia complicated by cardiac failure, pulmonary hypertension, and pericardial effusion: a case report. [PDF]

open access: yesJ Med Case Rep, 2023
Yousaf M   +8 more
europepmc   +1 more source

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