Results 231 to 240 of about 4,737,690 (404)

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

Exploring the Utility of Renal Resistive Index in Critical Care: Insights into ARDS and Cardiac Failure. [PDF]

Biomedicines
Cuttone G, Geraci G, La Via L, Sorbello M, Pappalardo F, Carollo C.   +5 more
europepmc   +1 more source

Berry syndrome: a rare cause of cardiac failure in the early neonatal period. [PDF]

BMJ Case Rep, 2022
Dias J, Marinho J, Rodrigues D, Pires A.
europepmc   +1 more source

PFKM‐Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation

Advanced Science, EarlyView.
The upregulation of PFKM activates glycolysis, thereby enhancing lactate production in atrial tissue. Atrial lactate accumulation promotes global lactylation and H3K18 lactylation in atrial fibroblasts. P300‐mediated H3K18 lactylation up‐regulates TGF‐β1 transcription, leading to fibroblast activation and thereby contributing to atrial fibrosis.
Ning Fang, Ning Zhang, Xiaohui Jiang, Sen Yan, Zhiqi Wang, Qianhui Gao, Mingcheng Xu, Lin Mu, Xiaoming Li, Jiuling Chen, Song Zhang, Yu Duan, Fengxiang Yun, Luyifei Li, Yun Zhang, Yongtai Gong   +15 more
wiley   +1 more source

Cumulative review of cardiac failure with acalabrutinib in the treatment of chronic lymphocytic leukemia using data from clinical trials and postmarketing experience. [PDF]

Hemasphere
Ghia P, Bajwa N, Corry AJ, Jannuru S, Kreuzbauer G, Pareek M.   +5 more
europepmc   +1 more source

At the heart of the problem: congestive cardiac failure as a cause of ascites: A narrative review. [PDF]

Medicine (Baltimore), 2022
Goh ZNL, Teo RYL, Chung BK, Wong AC, Seak CJ.   +4 more
europepmc   +1 more source

ASSISTED CIRCULATION FOR CARDIAC FAILURE FOLLOWING INTRACARDIAC SURGERY WITH CARDIOPULMONARY BYPASS

, 1965
Frank C. Spencer, Ben Eiseman, J. Kent Trinkle, Nicholas P. Rossi   +3 more
openalex   +1 more source

Cardiac Failure in Malignant Disease [PDF]

, 1965
Jacqueline J. Taylor
openalex   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Cardiac Failure and Cardiogenic Shock: Insights Into Pathophysiology, Classification, and Hemodynamic Assessment. [PDF]

Cureus
Siopi SA, Antonitsis P, Karapanagiotidis GT, Tagarakis G, Voucharas C, Anastasiadis K.   +5 more
europepmc   +1 more source