Results 241 to 250 of about 1,200,882 (301)

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

open access: yesAdvanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen   +11 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu   +6 more
wiley   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou   +8 more
wiley   +1 more source

Data Sheet 1_Development and validation of an interpretable machine learning model for predicting the risk of non-cardiac surgery postoperative heart failure: a multicenter study.docx

open access: green
Qing Li (84975)   +11 more
openalex   +1 more source

Cardiac Failure*

Journal of Small Animal Practice, 1967
Abstract— —The physiological mechanisms involved in increasing cardiac output are described and designated as the cardiac reserves. The utilization of these reserves in maintaining life when the heart is failing illustrates the origin of some of the clinical signs observed.
JOHN RENDLE-SHORT, O.P. GRAY
openaire   +3 more sources

Cardiac Pacemaker Failure

Annals of Internal Medicine, 1977
Excerpt Close follow-up of implanted cardiac pacemakers allows safe complete use of battery life.
C N, Leach, M J, Sands, S, Galle
openaire   +2 more sources

Integrated management of cardiac failure: the cardiac failure clinic

Frontiers of Medicine, 2011
The prevalence of the risk factors and the risk of cardiac failure are both increasing in China. This might be the consequence of the changes of the life conditions (emigration to the urban areas, changes in the diet and life style, lack of physical exercise, etc.).
openaire   +2 more sources

Cardiac Failure

Pediatrics In Review, 1980
Congestive heart failure is an altered state of circulatory dynamics resulting from an imbalance between the demands by the body for blood flow to meet its metabolic needs and the ability of the heart to meet those demands. The imbalance may be created in several different ways (Fig 1).
openaire   +1 more source

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