Results 251 to 260 of about 1,199,408 (314)

Repurposing Cardiac Glycosides to Potentiate CD47 Blockade through Calreticulin‐mediated Phagocytic Effects for Lung Cancer Treatment

open access: yesAdvanced Science, EarlyView.
Repurposing cardiac glycosides (CGs) significantly strengthens the efficacy of anti‐CD47 antibody for lung cancer treatment by boosting macrophage phagocytosis. This novel combination blocks the “don't eat me” signal and increases dual “eat‐me” signals, Fc‐FcγR and cell surface expression of calreticulin (ecto‐CRT).
Zi‐Han Ye   +9 more
wiley   +1 more source

Cardiac contractility modulation in patients with heart failure: The added value of cardiac rehabilitation in identification, management, and follow-up

open access: gold
Matteo Ruzzolini   +11 more
openalex   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

open access: yesAdvanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma   +5 more
wiley   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

open access: yesAdvanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini   +4 more
wiley   +1 more source

Preoperative right ventricular strain as an early predictor of perioperative cardiac failure in patients undergoing mitral surgery: An exploratory study. [PDF]

open access: yesHealth Sci Rep
Russo A   +14 more
europepmc   +1 more source

Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy

open access: green, 2014
Justin G. Lichter   +8 more
openalex   +2 more sources

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

open access: yesAdvanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang   +16 more
wiley   +1 more source

Jellyfish stings-induced cardiac failure was ameliorated through AAG-mediated glycogen-driven ATP production. [PDF]

open access: yesExploration (Beijing)
Qin Z   +12 more
europepmc   +1 more source

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