Results 301 to 310 of about 4,737,690 (404)

LncDARS‐AS1 Regulates ATP1A1 Stability and Enhances Na+/K+ ATPase Activity to Promote Osteosarcoma Metastasis

open access: yesAdvanced Science, EarlyView.
This study identifies LncDARS‐AS1 as a novel oncogenic regulator that stabilizes ATP1A1 and enhances Na⁺/K⁺ ATPase activity, promoting osteosarcoma metastasis. Targeting the LncDARS‐AS1/ATP1A1/NKA axis, including pharmacological inhibition with digoxin, offers promising opportunities for the development of new therapeutic strategies against ...
Mingxian Xu   +12 more
wiley   +1 more source

Cancer Therapy–Related Cardiac Dysfunction and Heart Failure: Part 1: Definitions, Pathophysiology, Risk Factors, and Imaging

open access: yesCirculation: Heart Failure, 2016
M. Bloom   +10 more
semanticscholar   +1 more source

Unraveling Tissue‐Specific Fatty Acid Biosynthesis and Inter‐Tissue Crosstalk in Mice through Stable‐Isotope Tracing Metabolomics

open access: yesAdvanced Science, EarlyView.
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing   +4 more
wiley   +1 more source

Jellyfish stings-induced cardiac failure was ameliorated through AAG-mediated glycogen-driven ATP production. [PDF]

open access: yesExploration (Beijing)
Qin Z   +12 more
europepmc   +1 more source

Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging

open access: yesAdvanced Science, EarlyView.
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu   +13 more
wiley   +1 more source

Oxygen utilization and ventilation during exercise in patients with chronic cardiac failure. [PDF]

open access: bronze, 1982
K. T. Weber   +3 more
openalex   +1 more source

Neutrophil–Endothelium Interaction Mediated by S100A9 Promotes Pulmonary Vascular Remodeling During Pulmonary Hypertension

open access: yesAdvanced Science, EarlyView.
This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy