Results 331 to 340 of about 4,737,690 (404)

Cancer Therapy–Related Cardiac Dysfunction and Heart Failure: Part 2: Prevention, Treatment, Guidelines, and Future Directions

Circulation: Heart Failure, 2016
C. Hamo, M. Bloom, D. Cardinale, B. Ky, A. Nohria, L. Baer, H. Skopicki, D. Lenihan, M. Gheorghiade, A. Lyon, J. Butler   +10 more
semanticscholar   +1 more source

Superelastic Fire‐Safe Aerogel with Hierarchical Structures via Dual Templates Aided by Microbubble Engineering

Advanced Science, EarlyView.
Here, a dual‐template strategy (ice and bubble template) is used to prepare fire‐safe aerogels with hierarchical structures. When the foam expansion ratio exceeds the jamming transition value in the foam system, the aerogels demonstrate superelasticity and extreme shape adaptability.
Xiaoyang Yu, Huan Li, Ning Kang, Shouxiang Lu, Mingjun Xu, Man Pun Wan   +5 more
wiley   +1 more source

Changes of Cardiac Performance in Renal Failure

, 1975
Tadao Uraoka, Tsuneaki Sugimoto, Tohru Inasaka, Kensuke Kaseno, Kunihiko Hirasawa, Shunsuke Kitagawa, Jugoro Takeuchi   +6 more
openalex   +2 more sources

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy

Advanced Science, EarlyView.
Programmable DNA framework captors effectively deplete circulatingtransforming growth factor‐β1 (TGFβ1) through fast systemic clearance and reshape the tumor immune microenvironment, alleviating immunosuppression to inhibit tumor progression. Abstract Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment ...
Xiao Chen, Dunfang Liu, Jiahui Jin, Han Yao, Yao Sheng, Yarong Liu, Jingwei Sun, Yang Yang   +7 more
wiley   +1 more source

Anti‐Icing Organogel Enables Quasi‐Homogeneous Supercooling Preservation of Mouse Hearts

Advanced Science, EarlyView.
An organogel interface with a large energy barrier for ice nucleation is proposed to enable a quasi‐homogeneous supercooling preservation for organs. This method does not rely on cryoprotectant agents or machine perfusion and can double the ex vivo storage time of mouse hearts.
Junhao Li, Wei Wang, Chenghao Li, Lintao Kuang, Zhi Huang, Xing Chen, Zhenghao Guo, Kang Liu, Jinping Liu   +8 more
wiley   +1 more source

Dual‐Graded Microstructure Engineering for Flexible Piezoresistive Sensors with High Sensitivity and Broad Linear Range in Physiological Monitoring

Advanced Science, EarlyView.
A flexible piezoresistive pressure sensor with dual‐graded microstructures achieves both high sensitivity (69.8 kPa⁻¹) and a broad linear range up to 300 kPa (R2 = 0.997). Synergizing structural deformation and tunneling conduction, it enables rapid, stable, and accurate detection of subtle physiological signals, offering a scalable and cost‐effective ...
Ningning Bai, Dandan Xu, Zhuang Su, Gangqiang Li, Lilong He, Yanli Chen, Chengxi Guo, Linxuan Zhou, Xianming Qin, Ji Zhang, Daowei Wu, Weidong Wang   +11 more
wiley   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

Modulation of plasma and platelet vasopressin by cardiac function in patients with heart failure

, 1986
Daniel G. Bichet, Claude Kortas, Bertrand Mettauer, Christiane Manzini, J Marc-Aurèle, Jean L. Rouleau, Robert W. Schrier   +6 more
openalex   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source