Results 41 to 50 of about 4,201,128 (311)
European Journal of Heart Failure, 2018 We tested the hypothesis that a machine learning (ML) algorithm utilizing both complex echocardiographic data and clinical parameters could be used to phenogroup a heart failure (HF) cohort and identify patients with beneficial response to cardiac ...
M. Čikeš +13 more
semanticscholar +1 more source
European Journal of Heart Failure, 2021 In this document, we propose a universal definition of heart failure (HF) as a clinical syndrome with symptoms and/or signs caused by a structural and/or functional cardiac abnormality and corroborated by elevated natriuretic peptide levels and/or ...
B. Bozkurt +37 more
semanticscholar +1 more source
Accounting for TLD response to CBCT protocols in external beam radiotherapy dose monitoring
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose LiF thermoluminescent dosimeters (TLDs) are commonly used in radiation therapy to verify the delivered dose. Examples include dose verification for complicated treatment setups or cardiovascular implantable electronic devices (CIEDs). TLDs may be present for both the pre‐treatment imaging kilovoltage (kV) beam and the megavoltage (MV ...
Andrew J. White +5 more
wiley +1 more source
Angiogenic Endothelial Cell Signaling in Cardiac Hypertrophy and Heart Failure
Frontiers in Cardiovascular Medicine, 2019 Endothelial cells are, by number, one of the most abundant cell types in the heart and active players in cardiac physiology and pathology. Coronary angiogenesis plays a vital role in maintaining cardiac vascularization and perfusion during physiological ...
Rajinikanth Gogiraju +2 more
semanticscholar +1 more source
Journal of Applied Clinical Medical Physics, EarlyView.Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye +16 more
wiley +1 more source
Advanced Biology, EarlyView.Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang +6 more
wiley +1 more source
Mechanotransduction in Cardiac Hypertrophy and Failure [PDF]
Circulation Research, 2015 Cardiac muscle cells have an intrinsic ability to sense and respond to mechanical load through a process known as mechanotransduction. In the heart, this process involves the conversion of mechanical stimuli into biochemical events that induce changes in myocardial structure and function.
Lyon, Robert C +3 more
openaire +5 more sources
Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure
Circulation, 2018 Background: Fibronectin (FN) polymerization is necessary for collagen matrix deposition and is a key contributor to increased abundance of cardiac myofibroblasts (MFs) after cardiac injury.
Íñigo Valiente-Alandí +15 more
semanticscholar +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
European Journal of Heart Failure, 2018 To assess adverse outcomes attributable to non‐cardiac co‐morbidities and to compare their effects by left ventricular ejection fraction (LVEF) group [LVEF
A. Iorio +11 more
semanticscholar +1 more source