Results 41 to 50 of about 4,730,641 (404)

Cardiac cellular diversity and functionality in cardiac repair by single-cell transcriptomics

Frontiers in Cardiovascular Medicine, 2023
Cardiac repair after myocardial infarction (MI) is orchestrated by multiple intrinsic mechanisms in the heart. Identifying cardiac cell heterogeneity and its effect on processes that mediate the ischemic myocardium repair may be key to developing novel ...
Wei Chen, Wei Chen, Chuling Li, Chuling Li, Yijin Chen, Yijin Chen, Jianping Bin, Jianping Bin, Yanmei Chen, Yanmei Chen, Yanmei Chen   +10 more
doaj   +1 more source

Hypocalcaemic cardiac failure [PDF]

Postgraduate Medical Journal, 1978
SummaryA 35-year-old patient who presented with recurrent chest infection, pulmonary oedema and cardiac failure was found to be grossly hypocalcaemic owing to previously undiagnosed hypoparathyroidism. The cardiac failure was not easily relieved by digoxin and diuretics but it quickly responded when the plasma calcium was restored to normal with ...
D. P. Brenton, A. B. Pollard, J. Gonzales   +2 more
openaire   +2 more sources

Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure

Circulation: Heart Failure, 2020
Supplemental Digital Content is available in the text. Background: Although empagliflozin was shown to profoundly reduce cardiovascular events in diabetic patients and blunt the decline in cardiac function in nondiabetic mice with established heart ...
Nikole J. Byrne, Nobutoshi Matsumura, Zaid H Maayah, M. Ferdaoussi, S. Takahara, Ahmed M Darwesh, Jody Levasseur, James Won Suk Jahng, D. Vos, N. Parajuli, A. El-Kadi, B. Braam, M. Young, S. Verma, P. Light, G. Sweeney, J. Seubert, J. Dyck   +17 more
semanticscholar   +1 more source

A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function

JACC: Basic to Translational Science, 2016
Myocardial infarction (MI) remains a dreadful disease around the world, causing irreversible sequelae that shorten life expectancy and reduce quality of life despite current treatment.
Isaac Perea-Gil, MS, Cristina Prat-Vidal, PhD, Carolina Gálvez-Montón, DVM, PhD, Santiago Roura, PhD, Aida Llucià-Valldeperas, PhD, Carolina Soler-Botija, PhD, Oriol Iborra-Egea, MS, Idoia Díaz-Güemes, DVM, PhD, Verónica Crisóstomo, DVM, PhD, Francisco M. Sánchez-Margallo, DVM, PhD, Antoni Bayes-Genis, MD, PhD   +10 more
doaj   +1 more source

Subclinical myocardial disease by cardiac magnetic resonance imaging and spectroscopy in healthy HIV/Hepatitis C virus-coinfected persons. [PDF]

, 2017
Objective The contribution of hepatitis C virus (HCV) infection to the risk of heart failure in human immunodeficiency virus (HIV)-coinfected persons is unknown.
Ambale-Venkatesh, Bharath, Bluemke, David A, Butt, Adeel A, Chew, Kara W, Currier, Judith S, Horwich, Tamara B, Liao, Diana, Lima, João AC, Liu, Chia-Ying, Paul Finn, J   +9 more
core   +2 more sources

Toward a solution for cardiac failure in the newborn

Xenotransplantation, 2018
The newborn infant with severe cardiac failure owed to congenital structural heart disease or cardiomyopathy poses a daunting therapeutic challenge. The ideal solution for both might be cardiac transplantation if availability of hearts was not limiting ...
J. Platt, L. West, R. Chinnock, M. Cascalho   +3 more
semanticscholar   +1 more source

Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials

BMC Cardiovascular Disorders, 2017
BackgroundThe therapeutic efficacy of coenzyme Q10 on patients with cardiac failure remains controversial. We pooled previous clinical studies to re-evaluate the efficacy of coenzyme Q10 in patients with cardiac failure.MethodsWe searched PubMed ...
L. Lei, Yan Liu
semanticscholar   +1 more source

A case report of recessive restrictive cardiomyopathy caused by a novel mutation in cardiac troponin I (TNNI3)

BMC Medical Genetics, 2019
Background Restrictive cardiomyopathy is a rare cardiac disease, for which several genes including TNNT2, MYPN, FLNC and TNNI3 have been associated with its familial form.
Malena P. Pantou, Polyxeni Gourzi, Aggeliki Gkouziouta, Iakovos Armenis, Loukas Kaklamanis, Christianna Zygouri, Pantelis Constantoulakis, Stamatis Adamopoulos, Dimitrios Degiannis   +8 more
doaj   +1 more source

Involvement in Health Behavior After Heart Transplantation: The Role of Personal Resources and Health Status. Single-Center Observational Study

Frontiers in Psychology, 2021
Introduction: Heart transplantation affects all spheres of the patients’ functioning - their physical well-being and coping with everyday situations, as well as their identity and social functioning.
Anna Mierzyńska, Anna Mierzyńska, Andrzej Kokoszka, Grażyna Jerzak-Wodzyńska, Małgorzata Sobieszczańska-Małek, Tomasz Zieliński, Ryszard Piotrowicz   +6 more
doaj   +1 more source

Normal versus pathological cardiac fibroblast-derived extracellular matrix differentially modulates cardiosphere-derived cell paracrine properties and commitment [PDF]

, 2017
Human resident cardiac progenitor cells (CPCs) isolated as cardiosphere-derived cells (CDCs) are under clinical evaluation as a therapeutic product for cardiac regenerative medicine.
Angelini, Francesco, BIONDI ZOCCAI, Giuseppe, Castaldo, Clotilde, Chimenti, Isotta, Frati, Giacomo, Maiello, Ciro, Meglio, Franca di, Messina, Elisa, Nurzynska, Daria, Pagano, Francesca, Picchio, Vittorio, Sciarretta, Sebastiano   +11 more
core   +7 more sources