Sca-1+ cardiac fibroblasts promote development of heart failure [PDF]
, 2018 The causative effect of GM-CSF produced by cardiac fibroblasts to development of heart failure has not been shown. We identified the pathological GM-CSF-producing cardiac fibroblast subset and the specific deletion of IL-17A signaling to these cells ...
Bracamonte-Baran, William +14 more
core +1 more source
Journal of Advanced Research, 2023 Introduction: Extracellular vesicles (EVs)-mediated cell-to-cell communication is crucial for hypoxia-induced cell proliferation and tissue repair, but its function in endogenous cardiac regeneration is still unknown.
Guoquan Wei +15 more
doaj
Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse [PDF]
, 2017 Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized ...
Abbate, A. +7 more
core +2 more sources
Practical approach on frail older patients attended for acute heart failure [PDF]
, 2016 Acute heart failure (AHF) is a multi-organ dysfunction syndrome. In addition to known cardiac dysfunction, non-cardiac comorbidity, frailty and disability are independent risk factors of mortality, morbidity, cognitive and functional decline, and risk of
Bueno, H +15 more
core +4 more sources
Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells. [PDF]
, 2015 The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor ...
Kim, Hyun Jin +5 more
core +3 more sources
Epigenetic Biomarkers in Cardiovascular Diseases
Frontiers in Genetics, 2019 Cardiovascular diseases are the number one cause of death worldwide and greatly impact quality of life and medical costs. Enormous effort has been made in research to obtain new tools for efficient and quick diagnosis and predicting the prognosis of ...
Carolina Soler-Botija +7 more
doaj +1 more source
Investigating the protective role of the natural hormone Melatonin, in reducing drug-induced cardiotoxicity in the therapy of chronic diseases [PDF]
, 2019 Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CVD). The pathogenesis of HF is mostly unresolved but involves interplay between cardiac structural and electrical remodelling, metabolic alterations, cell ...
Kasi Ganeshan, T., Kasi Ganeshan, T.
core
Simple new risk score model for adult cardiac extracorporeal membrane oxygenation: simple cardiac ECMO score. [PDF]
, 2015 BACKGROUND: Although the use of cardiac extracorporeal membrane oxygenation (ECMO) is increasing in adult patients, the field lacks understanding of associated risk factors. While standard intensive care unit risk scores such as SAPS II (simplified acute
Cavarocchi, Nicholas +3 more
core +2 more sources
Cardiac Function and Heart Failure
Journal of the American College of Cardiology, 2006 For the ACC.06 Scientific Sessions, the Program Committee received 736 submissions in the area of heart failure (HF), 244 of which were accepted for presentation. Although there were a limited number of large HF clinical trials, HF and cardiac function topics were well represented in various ...
Christopher M. O'Connor +2 more
openaire +3 more sources