Obesity and cardiac function. [PDF]
We studied 10 obese volunteers, mean age 36.5 +/- 10.3 years, who weighed 123.56 +/- 28.7 g and were 69.96 +/- 22.5 kg overweight. The subjects did not have diabetes, arterial hypertension or signs of cardiac and respiratory failure or disease and all underwent right- and left-heart catheterization. cardiac output and stroke volume were high, according
DE DIVITIIS O. +5 more
openaire +5 more sources
NO and cardiac diastolic function [PDF]
Time for primary review 34 days. Since the first report of a role for nitric oxide (NO) in modulating myocardial contractile function in 1991 [1], an enormous number of studies have been published in this field (recently reviewed in Refs. [2–4]). It is now recognised that, under physiological conditions, the major sources of NO that are important for
Walter Paulus, Ajay M. Shah
openaire +3 more sources
Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse [PDF]
Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized ...
Abbate, A. +7 more
core +2 more sources
Cardiac Rehabilitation and Endothelial Function [PDF]
Endothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the mechanisms of its beneficial effects remain only ...
Lanza, Gaetano Antonio +6 more
openaire +4 more sources
Subclinical myocardial disease by cardiac magnetic resonance imaging and spectroscopy in healthy HIV/Hepatitis C virus-coinfected persons. [PDF]
Objective The contribution of hepatitis C virus (HCV) infection to the risk of heart failure in human immunodeficiency virus (HIV)-coinfected persons is unknown.
Ambale-Venkatesh, Bharath +9 more
core +2 more sources
Cardiac cellular diversity and functionality in cardiac repair by single-cell transcriptomics
Cardiac repair after myocardial infarction (MI) is orchestrated by multiple intrinsic mechanisms in the heart. Identifying cardiac cell heterogeneity and its effect on processes that mediate the ischemic myocardium repair may be key to developing novel ...
Wei Chen +10 more
doaj +1 more source
Impaired cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with Barth syndrome [PDF]
Barth syndrome (BTHS) is an X‐linked condition characterized by altered cardiolipin metabolism and cardioskeletal myopathy. We sought to compare cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with BTHS and unaffected
Altschuld +61 more
core +2 more sources
Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart [PDF]
With aging, there is a decline in cardiac function accompanying increasing risk of arrhythmias. These effects are likely to be mechanistically associated with age-associated changes in calcium regulation within cardiac myocytes.
Close, Graeme L. +6 more
core +2 more sources
CARDIAC FUNCTIONAL TESTS [PDF]
The Eldorado of a cardiologist would be some test or combination of tests which would definitely determine the functional capacity of a given heart. This has been long sought, but is still an accomplishment for the future. The methods which have been devised and reported may be roughly classed as exercise tests, respiratory tests, tests based on the ...
Paul D. White, Harold H. Brittingham
openaire +2 more sources
Cardiac function in hyperthyroidism [PDF]
AbstractIt is accepted that thyroid hormones, thyrox‐ine and tri‐iodothyronine have direct inotropic and chronotropic effects on the heart. However, the mechanisms of manifestations are still uncertain. The following discusses and evaluates some of the theories regarding the interaction of these hormones with cardiac function.
Abdulmassih S. Iskandrian +3 more
openaire +3 more sources

