Results 11 to 20 of about 1,546,717 (359)

Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse [PDF]

, 2017
Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized ...
Abbate, A., Buzzetti, Raffaella, Carbone, Salvatore, Lee, P. J. H., Mauro, A. G., Mezzaroma, E., Toldo, S., Van Tassell, B.   +7 more
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Subclinical myocardial disease by cardiac magnetic resonance imaging and spectroscopy in healthy HIV/Hepatitis C virus-coinfected persons. [PDF]

, 2017
Objective The contribution of hepatitis C virus (HCV) infection to the risk of heart failure in human immunodeficiency virus (HIV)-coinfected persons is unknown.
Ambale-Venkatesh, Bharath, Bluemke, David A, Butt, Adeel A, Chew, Kara W, Currier, Judith S, Horwich, Tamara B, Liao, Diana, Lima, João AC, Liu, Chia-Ying, Paul Finn, J   +9 more
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Magnetic resonance imaging of myocardial strain after acute ST-segment-elevation myocardial infarction: a systematic review [PDF]

, 2017
The purpose of this systematic review is to provide a clinically relevant, disease-based perspective on myocardial strain imaging in patients with acute myocardial infarction or stable ischemic heart disease.
Auger, Daniel A., Berry, Colin, Epstein, Frederick H., Mangion, Kenneth, McComb, Christie   +4 more
core   +1 more source

Cardiac cellular diversity and functionality in cardiac repair by single-cell transcriptomics

Frontiers in Cardiovascular Medicine, 2023
Cardiac repair after myocardial infarction (MI) is orchestrated by multiple intrinsic mechanisms in the heart. Identifying cardiac cell heterogeneity and its effect on processes that mediate the ischemic myocardium repair may be key to developing novel ...
Wei Chen, Wei Chen, Chuling Li, Chuling Li, Yijin Chen, Yijin Chen, Jianping Bin, Jianping Bin, Yanmei Chen, Yanmei Chen, Yanmei Chen   +10 more
doaj   +1 more source

Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. [PDF]

, 2019
With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Agrawal, Azakie, Baio, Becker, Bergmann, Burridge, Camberos, Connor, Drosatos, Fermini, Fritsch-Yelle, Garrett-Bakelman, Gauthier, Huebsch, Hughson, Jha, Kim, Kwon, Oikonomopoulos, Perhonen, Rogers, Sharma, Sharma, Sharma, Sides, Spotnitz, Sun, Thomason, Wnorowski, Wu, Yu   +30 more
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Impaired cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with Barth syndrome [PDF]

, 2017
Barth syndrome (BTHS) is an X‐linked condition characterized by altered cardiolipin metabolism and cardioskeletal myopathy. We sought to compare cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with BTHS and unaffected
Altschuld, American College of Sports Medicine, Bahi, Barth, Bashir, Bione, Bissler, Cade, Cade, Chance, Chance, Conway, Edwards, El-Sharkawy, Gomez, Gonzalvez, Hiona, Hom, Hudsmith, Ingwall, Kemp, Kemp, Kemp, Kemp, Kushmerick, Lang, Lanza, Lanza, Larson-Meyer, Layec, Liu, Matthews, Meyer, Meyer, Minotti, Naressi, Nascimben, Neubauer, Powers, Ratel, Roussel, Sapega, Schlame, Sgobbo, Smith, Spencer, Spencer, Spoladore, Takahashi, Taylor, Taylor, Thaveau, Thompson, Tonson, Vanhamme, Wang, Wasserman, Waters, Xu, Yao, Zhang, Zoll   +61 more
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Integrated photothermal decontamination device for N95 respirators

Scientific Reports, 2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in the death of millions.
Marcelo Muñoz, Maxime Comtois-Bona, David Cortes, Cagla Eren Cimenci, Qiujiang Du, Collin Thompson, Juan David Figueroa, Vivian Franklin, Peter Liu, Emilio I. Alarcon   +9 more
doaj   +1 more source

LDHA-mediated metabolic reprogramming promoted cardiomyocyte proliferation by alleviating ROS and inducing M2 macrophage polarization

Redox Biology, 2022
Aims: Metabolic switching during heart development contributes to postnatal cardiomyocyte (CM) cell cycle exit and loss of regenerative capacity in the mammalian heart. Metabolic control has potential for developing effective CM proliferation strategies.
Yijin Chen, Guangkai Wu, Mengsha Li, Michael Hesse, Yusheng Ma, Wei Chen, Haoxiang Huang, Yu Liu, Wenlong Xu, Yating Tang, Hao Zheng, Chuling Li, Zhongqiu Lin, Guojun Chen, Wangjun Liao, Yulin Liao, Jianping Bin, Yanmei Chen   +17 more
doaj   +1 more source

The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice [PDF]

, 2018
BACKGROUND: The orphan receptor G protein–coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure.
Divorty, Nina, Graham, Delyth, Milligan, Graeme, Nicklin, Stuart A.   +3 more
core   +1 more source

Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway

Journal of Advanced Research, 2023
Introduction: Extracellular vesicles (EVs)-mediated cell-to-cell communication is crucial for hypoxia-induced cell proliferation and tissue repair, but its function in endogenous cardiac regeneration is still unknown.
Guoquan Wei, Chuling Li, Xiaoqian Jia, Jingfang Xie, Zhenquan Tang, Ming Jin, Qiqi Chen, Yili Sun, Sisi He, Xinzhong Li, Yanmei Chen, Hao Zheng, Wangjun Liao, Yulin Liao, Jianping Bin, Senlin Huang   +15 more
doaj   +1 more source