Results 31 to 40 of about 1,502,760 (361)

Establishment and Clinical Application of a RPA-LFS Assay for Detection of Capsulated and Non-Capsulated Haemophilus influenzae

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
A recombinase polymerase amplification-lateral flow strip assay was established for detection of the outer membrane protein P6 (omp6) and the capsule encoding gene bexA of Haemophilus influenzae and the detection limit, sensitivity, and specificity were ...
Yan Wang   +6 more
doaj   +1 more source

Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. [PDF]

open access: yes, 2019
With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Agrawal   +30 more
core   +1 more source

A bioprinted cardiac patch composed of cardiac-specific extracellular matrix and progenitor cells for heart repair [PDF]

open access: yes, 2018
Congenital heart defects are present in 8 of 1000 newborns and palliative surgical therapy has increased survival. Despite improved outcomes, many children develop reduced cardiac function and heart failure requiring transplantation.
Bejleri, Donald   +6 more
core   +1 more source

Direct assessment of cardiac function. [PDF]

open access: bronzeBritish Journal of Clinical Pharmacology, 1978
In the assessment of the effects of drugs on the heart it is important to define the aspects of cardiac function to be measured. We seem to be coming through a period of philosophical revision of our understanding of cardiac function and a new consensus is beginning to appear.
John Hamer
openalex   +6 more sources

Training-induced gene expression plasticity in cardiac function and neural regulation for ultra-trail runners [PDF]

open access: yes, 2015
This study aims to assess the gene regulatory response from a group of 16 athletes and to observe the plasticity induced by their training regime on the gene expression response after their participation in an 82km race.
Brotons, Daniel   +4 more
core   +1 more source

Cardiac structure and function

open access: yesJournal of the American College of Cardiology, 2004
In the cardiac function and heart failure category, 1,143 abstracts were submitted and 377 accepted for presentation. For clarity, this manuscript will be divided into a number of different highlight subcategories.
openaire   +3 more sources

The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice [PDF]

open access: yes, 2018
BACKGROUND: The orphan receptor G protein–coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure.
Divorty, Nina   +3 more
core   +1 more source

Thrombospondin-1 Silencing Ameliorates Osteoblastic Differentiation of Aortic Valve Interstitial Cells via Inhibiting Nuclear Factor-κB Pathway

open access: yesCardiovascular Therapeutics
Conclusions: The present study has shown that TSP-1 silencing could mitigate the development of CAVD by inhibiting NF-κB-mediated inflammation. We propose that targeting TSP-1-mediated NF-κB pathway could provide a potential therapeutic method for ...
Qing Li   +9 more
doaj   +1 more source

M2 macrophage-derived exosome-modified bioprosthetic heart valves with enhanced anti-inflammatory, anticoagulant and anticalcification properties

open access: yesMaterials & Design
Glutaraldehyde (Glut) cross-linked bioprosthetic heart valves (BHVs) have shown great performance in the replacement treatment of severe valvular heart diseases in recent years due to the rapid development of transcatheter aortic valve replacement (TAVR)
Jingruo Chen   +8 more
doaj   +1 more source

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