Results 81 to 90 of about 1,502,760 (361)
JACC: Case Reports, 2020 A 58-year-old woman with drug-refractory symptoms of paroxysmal atrial fibrillation (AF) was referred for AF ablation. A single site of ganglionated plexus triggering pulmonary vein ectopy and AF was ablated, without pulmonary vein isolation.
Min-Young Kim, MBChB +5 more
doaj +1 more source
Cardiac hypertrophy and heart failure: from the case to review of literature [PDF]
, 2016 In response to an increased workload due to physiological or pathological stimuli, the heart may undergo a process of growth with increased muscle mass called cardiac hypertrophy. It is a particular mechanism of long term compensation used by the heart
Massoni, Francesco +4 more
core +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
Mechanical circulatory support as bridge therapy for heart transplant: case series report
BMC Research Notes, 2018 Background Mechanical circulatory support (MCS) represents an effective urgent therapy for patients with cardiac arrest or end-stage cardiac failure.
Javier D. Garzon-Rodriguez +5 more
doaj +1 more source
Nature Communications, 2023 Extracellular vesicles have shown good potential in disease treatments including ischemic injury such as myocardial infarction. However, the efficient production of highly active extracellular vesicles is one of the critical limitations for their ...
Bin Yu +11 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang +16 more
wiley +1 more source
BMC Anesthesiology, 2022 Background Dexmedetomidine has controversial influence on cardiac electrophysiology. The aim of this study was to explore the effects of dexmedetomidine on perioperative cardiac electrophysiology in patients undergoing general anesthesia.
Chao Tan +9 more
doaj +1 more source
Quadriscupid aortic valve with concurrent aortic stenosis and insufficiency [PDF]
, 2016 We present the case of a 22-year-old man with a congenital mixed aortic valve dysfunction who underwent cardiac Magnetic Resonance Imaging (MRI) for the assessment of aortic valve morphology and function prior to valve replacement.
Devos, Daniel +2 more
core +3 more sources
Mechanosensing and Regulation of Cardiac Function [PDF]
Journal of Clinical & Experimental Cardiology, 2014 The role of mechanical force as an important regulator of structure and function of mammalian cells, tissues, and organs has recently been recognized. However, mechanical overload is a pathogenesis or comorbidity existing in a variety of heart diseases, such as hypertension, aortic regurgitation and myocardial infarction.
Damir Nizamutdinov +10 more
openaire +3 more sources
The Diverse Neuromuscular Spectrum of VPS13A Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger +16 more
wiley +1 more source