Results 31 to 40 of about 356,411 (312)

Site-Directed Mutagenesis and Site-Specific Binding Analysis of Calmodulin (CaM) [PDF]

open access: yes, 2017
Calcium signaling is a major regulatory system in cells and a crucial part of cell biology. An important element in the decoding of intracellular calcium concentration into downstream processes is the ubiquitous and highly conserved calcium binding ...
Dokic, Yelena
core   +1 more source

Novel model predicts diastolic cardiac dysfunction in type 2 diabetes

open access: yesAnnals of Medicine, 2023
Objective Diabetes mellitus complicated with heart failure has high mortality and morbidity, but no reliable diagnoses and treatments are available.
Mingyu Hao   +8 more
doaj   +1 more source

Evolutionary Covariant Positions within Calmodulin EF-hand Sequences Promote Ligand Binding [PDF]

open access: yes, 2018
Intracellular calcium signaling is an essential regulatory mechanism through calcium-mediated signal transduction pathways involved in many cell processes, such as exocytosis, motility, apoptosis, excitability, transcription, and muscle contraction.
Vaidyanathan, Uma
core   +1 more source

Assessment of Left Atrial Deformation and Function by 2-Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease [PDF]

open access: yes, 2017
open7noBackground: The assessment of left atrial (LA) function by 2-dimensional speckle tracking echocardiography (STE) holds important clinical implications in human medicine. Few similar data are available in dogs.
Baron Toaldo, M.   +6 more
core   +2 more sources

Modeling the Heart as a Communication System [PDF]

open access: yes, 2014
Electrical communication between cardiomyocytes can be perturbed during arrhythmia, but these perturbations are not captured by conventional electrocardiographic metrics.
Aguilar-Rodríguez, José   +7 more
core   +2 more sources

Impact of Thyroid Dysfunction on Cardiac Structure and Function in Patients with Coronary Artery Disease Post-percutaneous Coronary Intervention: a Large Single-center Retrospective Cohort Study [PDF]

open access: yesZhongguo quanke yixue
Background Thyroid dysfunction is common in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI). However, its impact on cardiac structure and function within the context of chronic comorbidities remains unclear.
WANG Kaiyang, YU Xiaolin, MA Ling, TAO Jing, YONG Jiahui, YANG Yining
doaj   +1 more source

Enhanced Detection of Cardiac Surgery-Associated Acute Kidney Injury by a Composite Biomarker Panel in Patients with Normal Preoperative Kidney Function

open access: yesJournal of Cardiovascular Development and Disease, 2022
We have recently shown that minor subclinical creatinine dynamic changes enable the excellent detection of acute kidney injury (AKI) within 6–12 h after cardiac surgery.
Jurij Matija Kalisnik   +7 more
doaj   +1 more source

Evolution of spiral and scroll waves of excitation in a mathematical model of ischaemic border zone [PDF]

open access: yes, 2011
Abnormal electrical activity from the boundaries of ischemic cardiac tissue is recognized as one of the major causes in generation of ischemia-reperfusion arrhythmias. Here we present theoretical analysis of the waves of electrical activity that can rise
A Arutunyan   +45 more
core   +4 more sources

Effect of pulmonary artery systolic pressure on super-response and prognosis in patients after cardiac resynchronization therapy

open access: yesDi-san junyi daxue xuebao, 2019
Objective To evaluate the impact of baseline pulmonary artery systolic pressure (PASP) on cardiac function, left ventricle reverse remodeling and clinical outcomes in patients receiving cardiac resynchronization therapy (CRT).
GUO Zhinian   +4 more
doaj   +1 more source

Underestimated prognostic value of depression in patients with obstructive coronary artery disease

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectiveThe aim of this study was to explore the different predictive values of depression among patients with different cardiac systolic function levels.MethodsFour hundred eighty-three consecutive patients with obstructive coronary artery disease (CAD)
Quanjun Liu   +19 more
doaj   +1 more source

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