Results 31 to 40 of about 846,406 (342)

Heart Rate Variability for Early Detection of Cardiac Iron Deposition in Patients with Transfusion-Dependent Thalassemia. [PDF]

PLoS ONE, 2016
Iron overload cardiomyopathy remains the major cause of death in patients with transfusion-dependent thalassemia. Cardiac T2* magnetic resonance imaging is costly yet effective in detecting cardiac iron accumulation in the heart.
Suchaya Silvilairat, Pimlak Charoenkwan, Suwit Saekho, Adisak Tantiworawit, Arintaya Phrommintikul, Somdet Srichairatanakool, Nipon Chattipakorn   +6 more
doaj   +1 more source

Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance

European Heart Journal, 2020
Aims  Left ventricular (LV) failure in left bundle branch block is caused by loss of septal function and compensatory hyperfunction of the LV lateral wall (LW) which stimulates adverse remodelling.
J. Aalen, E. Donal, C. Larsen, J. Duchenne, M. Lederlin, M. Cvijić, A. Hubert, G. Voros, C. Leclercq, J. Bogaert, E. Hopp, J. Fjeld, M. Penicka, C. Linde, O. Aalen, E. Kongsgård, E. Galli, J. Voigt, O. Smiseth   +18 more
semanticscholar   +1 more source

Afterload-related cardiac performance is a powerful hemodynamic predictor of mortality in patients with chronic heart failure

Therapeutic Advances in Chronic Disease, 2023
Background: Afterload-related cardiac performance (ACP), a diagnostic parameter for septic cardiomyopathy, integrates both cardiac performance and vascular effects and could predict prognosis in septic shock.
Yihang Wu, Pengchao Tian, Lin Liang, Yuyi Chen, Jiayu Feng, Boping Huang, Liyan Huang, Xuemei Zhao, Jing Wang, Jingyuan Guan, Xinqing Li, Yuhui Zhang, Jian Zhang   +12 more
doaj   +1 more source

Novel model predicts diastolic cardiac dysfunction in type 2 diabetes

Annals of Medicine, 2023
Objective Diabetes mellitus complicated with heart failure has high mortality and morbidity, but no reliable diagnoses and treatments are available.
Mingyu Hao, Xiaohong Huang, Xueting Liu, Xiaokang Fang, Haiyan Li, Lingbo Lv, Liming Zhou, Tiecheng Guo, Dewen Yan   +8 more
doaj   +1 more source

Site-Directed Mutagenesis and Site-Specific Binding Analysis of Calmodulin (CaM) [PDF]

, 2017
Calcium signaling is a major regulatory system in cells and a crucial part of cell biology. An important element in the decoding of intracellular calcium concentration into downstream processes is the ubiquitous and highly conserved calcium binding ...
Dokic, Yelena
core   +1 more source

Evolutionary Covariant Positions within Calmodulin EF-hand Sequences Promote Ligand Binding [PDF]

, 2018
Intracellular calcium signaling is an essential regulatory mechanism through calcium-mediated signal transduction pathways involved in many cell processes, such as exocytosis, motility, apoptosis, excitability, transcription, and muscle contraction.
Vaidyanathan, Uma
core   +1 more source

Underestimated prognostic value of depression in patients with obstructive coronary artery disease

Frontiers in Cardiovascular Medicine, 2022
ObjectiveThe aim of this study was to explore the different predictive values of depression among patients with different cardiac systolic function levels.MethodsFour hundred eighty-three consecutive patients with obstructive coronary artery disease (CAD)
Quanjun Liu, Quanjun Liu, Han Yin, Cheng Jiang, Mingyu Xu, Mingyu Xu, Yuting Liu, Anbang Liu, Anbang Liu, Haochen Wang, Bingqing Bai, Bingqing Bai, Fengyao Liu, Fengyao Liu, Lan Guo, Lan Guo, Huan Ma, Huan Ma, Qingshan Geng, Qingshan Geng   +19 more
doaj   +1 more source

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]

, 2019
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko, Chang, Po-Cheng, Chen, Hanying, Chen, Peng-Sheng, Fishbein, Michael C., Homsi, Mohamed, Li, Bai-Yan, Lin, Shien-Fong, Liu, Jijia, Liu, Ying, Maruyama, Mitsunori, Pan, Zhenwei, Rubart, Michael, Shou, Weinian, Xiao, Deyong   +14 more
core   +1 more source

Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions

Genetics in Medicine, 2020
Accurate discrimination of benign and pathogenic rare variation remains a priority for clinical genome interpretation. State-of-the-art machine learning variant prioritization tools are imprecise and ignore important parameters defining gene–disease ...
Xiaolei Zhang, R. Walsh, N. Whiffin, R. Buchan, W. Midwinter, Alicja E Wilk, R. Govind, Nicholas Li, Mian Ahmad, F. Mazzarotto, Angharad M. Roberts, P. Theotokis, Erica Mazaika, M. Allouba, A. de Marvao, C. Pua, S. Day, E. Ashley, S. Colan, M. Michels, A. Pereira, D. Jacoby, Carolyn Y. Ho, I. Olivotto, G. Gunnarsson, J. Jefferies, C. Semsarian, J. Ingles, D. O’Regan, Yasmine Aguib, M. Yacoub, S. Cook, P. Barton, L. Bottolo, J. Ware   +34 more
semanticscholar   +1 more source

Impact of Thyroid Dysfunction on Cardiac Structure and Function in Patients with Coronary Artery Disease Post-percutaneous Coronary Intervention: a Large Single-center Retrospective Cohort Study [PDF]

Zhongguo quanke yixue
Background Thyroid dysfunction is common in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI). However, its impact on cardiac structure and function within the context of chronic comorbidities remains unclear.
WANG Kaiyang, YU Xiaolin, MA Ling, TAO Jing, YONG Jiahui, YANG Yining
doaj   +1 more source