Results 51 to 60 of about 356,411 (312)

Segmentation of the evolving left ventricle by learning the dynamics [PDF]

, 2008
We propose a method for recursive segmentation of the left ventricle (LV) across a temporal sequence of magnetic resonance (MR) images. The approach involves a technique for learning the LV boundary dynamics together with a particle-based inference ...
Cetin, Mujdat, Chan, Ray, Sun, Walter, Willsky, Alan S., Çetin, Müjdat   +4 more
core   +2 more sources

Effects of severe scoliosis on cardiac structure and function in resting patients: a retrospective study

Journal of Orthopaedic Surgery and Research
Background Severe scoliosis may impair cardiac structure and function. This study aims to evaluate the cardiac structural and functional changes in patients with severe thoracic scoliosis at rest, using echocardiography to inform perioperative strategies.
Jie Xiao, Tao Li, Yingsong Wang, Zhi Zhao, Jingming Xie, Jin Zhou   +5 more
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Longitudinal Changes in Cardiac Structure and Function in Severe Obesity: 11‐Year Follow‐Up in the Utah Obesity Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Progressive cardiac remodeling and worsening myocardial function over time have been proposed as potential mediators of heart failure in obesity.
Sheldon E. Litwin, Ted D. Adams, Lance E. Davidson, Rodrick McKinlay, Steven C. Simper, Lauren Ranson, Steven C. Hunt   +6 more
doaj   +1 more source

Abnormal Myocardial Blood Flow Reserve Observed in Cardiac Amyloidosis [PDF]

, 2016
We performed real-time myocardial contrast echocardiography on a patient with cardiac amyloidosis and previous normal coronary angiography presenting with atypical chest pain to assess myocardial blood flow reserve (MBFR).
Greaves, K, Nam, MC, Nel, K, Senior, R
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Functional Significance of Cardiac Rehabilitation-Regulated Expression of Circulating MicroRNA-423-5p in Hypertensive Patients with Heart Failure with a Moderately Reduced Ejection Fraction

Anatolian Journal of Cardiology, 2022
Background: Hypertension is a vital risk factor for heart failure, while cardiac rehabilitation can effectively improve cardiac function of heart failure patients.
Ying Huang, Yun Zhang, Wenzheng Nong, Biyang Lan, Dingmin Zhang   +4 more
doaj   +1 more source

Goal-directed therapy in intraoperative fluid and hemodynamic management. [PDF]

, 2013
Intraoperative fluid management is pivotal to the outcome and success of surgery, especially in high-risk procedures. Empirical formula and invasive static monitoring have been traditionally used to guide intraoperative fluid management and assess volume
Gutierrez, Maria Cristina, Liu, Hong, Moore, Peter G   +2 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source