Results 191 to 200 of about 461,431 (268)

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Toward Standardized Cardiac Imaging in Obstetric Care: The Need for Pregnancy-Specific Echocardiographic Reference Values. [PDF]

J Am Soc Echocardiogr
Adedinsewo D, Minhas AS, Mahmoud Z, Young KA, Williams MS.   +4 more
europepmc   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

The Evolving Role of Cardiac Imaging in Hypertrophic Cardiomyopathy: Diagnosis, Prognosis, and Clinical Practice. [PDF]

Biomedicines
Dentamaro I, Dicorato MM, Falagario A, Cicco S, Dentamaro S, Correale M, Manuppelli V, Citarelli G, Mangini F, Fiore C, Colonna P, Petruccelli E, Piscitelli L, Giovannetti G, Latorre MD, Forleo C, Basile P, Carella MC, Santobuono VE, Ciccone MM, Guaricci AI.   +20 more
europepmc   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source

Multifrequency Time-Dependent Deep Image Prior for Real-Time Free-Breathing Cardiac Imaging. [PDF]

NMR Biomed
Hamilton JI, Cruz G, Truesdell W, Agarwal P, Rashid I, Seiberlich N.   +5 more
europepmc   +1 more source

Cardiac radionuclide imaging.

Nihon Naika Gakkai Zasshi, 1988
openaire   +3 more sources

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through in Situ Differentiation and Morphogenesis of iPSCs

Advanced Science, EarlyView.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick, Juhi Chakraborty, Orlaith Kennedy, Hey Wei Wong, Sogol Kianersi, Daniel Kelly, Vasileios Sergis, Abhay Pandit, Andrew C. Daly   +8 more
wiley   +1 more source

Flurpiridaz F18: a new era in nuclear cardiac imaging - the first FDA-approved radiotracer in 30 years. [PDF]

Ann Med Surg (Lond)
Ayalew BD, Khaliq N, Marsool AD, Kashif A, Ahmedelhadi EM, Seid FF, Ul-Haq MA, Teweldeberhan A, Smith DN.   +8 more
europepmc   +1 more source