Results 31 to 40 of about 454,142 (307)

Left Atrial 4D Flow Characteristics in Patients with Atrial Fibrillation: Comparison with Healthy Controls and Associations with Left Atrial Remodelling and Contractile Health

Applied Sciences
Left atrial (LA) four-dimensional (4D) flow quantification and strain may help predict stroke and thrombus formation in patients with atrial fibrillation (AF). We aimed to characterize flow changes in AF patients undergoing pulmonary vein isolation (PVI)
Hana Sheitt, Dina Labib, Alena Yakimenka, Malcolm L. Serran, Steven Dykstra, Jacqueline Flewitt, Stephen B. Wilton, Sandra Rivest, James A. White, Julio Garcia   +9 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Imaging Techniques for the Assessment of Coronary Arteries in Diabetic Patients Undergoing PCI with Bioresorbable Vascular Scaffolds

Journal of Interdisciplinary Medicine, 2017
Patients who suffer from diabetes mellitus and present coronary artery disease are at a higher risk of cardiovascular events. The coronary arteries of diabetic patients present a diffuse process of atherosclerosis with frequent distal involvement, being ...
Cordunean Alina, Hodas Roxana, Benedek Edvin, Bordi Lehel, Benedek Imre, Benedek Theodora   +5 more
doaj   +1 more source

Influence of Sex-Based Differences in Cardiac Phenotype on Atrial Fibrillation Recurrence in Patients Undergoing Pulmonary Vein Isolation

Frontiers in Cardiovascular Medicine, 2022
BackgroundPulmonary vein isolation (PVI) is a commonly engaged therapy for symptomatic atrial fibrillation (AF). Prior studies have documented elevated AF recurrence rates among females vs. males.
Alena Yakimenka, Alena Yakimenka, Dina Labib, Dina Labib, Steven Dykstra, Yoko Mikami, Alessandro Satriano, Jacqueline Flewitt, Patricia Feuchter, Sandra Rivest, Andrew G. Howarth, Andrew G. Howarth, Carmen P. Lydell, Carmen P. Lydell, F. Russell Quinn, Stephen B. Wilton, James A. White, James A. White   +17 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Magnetic Resonance Imaging of Intramyocardial Fat Deposition in Tuberous Sclerosis

Diagnostics, 2020
Tuberous sclerosis complex (TSC) is a rare autosomal dominant neurocutaneous syndrome. The phenotype is highly variable and may affect several organ systems, the hallmark of the disease being widespread hamartomas or abnormal growth of normal tissues ...
Zoi Tsoumani, Melanie Greaves, Matthias Schmitt, Gaetano Nucifora   +3 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Cardiac Magnetic Resonance and Myocardial Viability: Why Is It so Important?

Journal of Interdisciplinary Medicine, 2017
For a better assessment of ischemic heart diseases, myocardial viability should be quantified. Current studies underline the importance and the evolution of several techniques and methods used in the evaluation of myocardial viability.
Rodean Ioana, Beganu Elena, Hodas Roxana, Himcinschi Elisabeta, Bordi Lehel, Benedek Theodora   +5 more
doaj   +1 more source

Time-dependent reversal of significant intrapulmonary shunt after liver transplantation [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Although the association between intrapulmonary shunt (IPS) and liver cirrhosis is clear, data of repeated contrast echocardiography (CE) before and after liver transplantation (LT) to evaluate factors associated with IPS are limited ...
Xin Jin, Byung Joo Sun, Jae-Kwan Song, Jae-Hyung Roh, Jeong Yoon Jang, Dae-Hee Kim, Young-Suk Lim, Jong-Min Song, Duk-Hyun Kang, Sung Gyu Lee   +9 more
doaj   +1 more source