Results 111 to 120 of about 470,992 (309)

Prospective assessment of different indices of cardiac risk for patients undergoing noncardiac surgeries

Arquivos Brasileiros de Cardiologia, 2002
OBJECTIVE: To compare the accuracy of 4 different indices of cardiac risk currently used for predicting perioperative cardiac complications. METHODS: We studied 119 patients at a university-affiliated hospital whose cardiac assessment had been required ...
Roberto Henrique Heinisch, Caroline Ferrari Barbieri, João Rogério Nunes Filho, Glauce Lippi de Oliveira, Liana Miriam Miranda Heinisch   +4 more
doaj   +1 more source

EEG Spectral Exponents and Visual Chirp Responses Mirror Anti‐Seizure Medication Load in Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Quantitative markers of cortical excitability may help identify responders to anti‐seizure medications (ASMs). We studied the relationship between ASM load and two electroencephalography (EEG) markers of cortical excitability in people with refractory epilepsy. Methods We included individuals with refractory focal epilepsy undergoing
Silvano R. Gefferie, Arthur R. van Nieuw Amerongen, Gerhard H. Visser, Maeike Zijlmans, Else A. Tolner, Mark van de Ruit, Arn M. J. M. van den Maagdenberg, Roland D. Thijs   +7 more
wiley   +1 more source

Indexed donor cardiac output for improved size matching in heart transplantation: A United Network for Organ Sharing database analysisCentral MessagePerspective

JTCVS Open, 2023
Objective: Implantation of an appropriately sized donor heart is critical for optimal outcomes after heart transplantation. Although predicted heart mass has recently gained consideration, there remains a need for improved granularity in size matching ...
Chetan Pasrija, MD, Zachary N. Kon, MD, Aakash Shah, MD, Sari D. Holmes, PhD, Karina S. Rozenberg, BS, Susan Joseph, MD, Bartley P. Griffith, MD   +6 more
doaj  

Clinical Trial Readiness in Limb Girdle Muscular Dystrophy R1 (LGMDR1): A GRASP Consortium Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying functional measures that are both valid and reliable in the limb girdle muscular dystrophy (LGMD) population is critical for quantifying the level of functional impairment related to disease progression in order to establish clinical trial readiness in the context of anticipated therapeutic trials.
Stephanie M. Hunn, Lindsay N. Alfano, Aileen Jones, Amanda Butler, Linda P. Lowes, Megan A. Iammarino, Natalie F. Reash, Lindsay Pietruszewski, Sandhya Sasidharan, Melissa Currence, Jeffrey M. Statland, Talia Strahler, Robert Will, Matthew Wicklund, Stacy Dixon, Renee Augsburger, Tahseen Mozaffar, Katie M. Laubscher, Shelley R. H. Mockler, Katherine D. Mathews, Nikia Stinson, Doris G. Leung, Molly M. Stark, Rebecca A. Horton, Peter B. Kang, Meredith K. James, Amanda Clause, Conrad C. Weihl, Nicholas E. Johnson, GRASP‐LGMD Consortium   +29 more
wiley   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

PULMONARY VASCULAR RESPONSE TO INCREASING CARDIAC INDEX FOLLOWING SYSTEMIC HYPOTENSION IS MODIFIED BY PENTOBARBITAL ANESTHESIA [PDF]

, 1987
Daniel Nyhan, Bessie B. Chen, Harold M Coll, P. W. Clougherty, Paul A. Murray   +4 more
openalex   +1 more source

Proteomic Profiling of SGLT-2 Inhibitor Canagliflozin in a Swine Model of Chronic Myocardial Ischemia

Biomedicines
Background: Sodium–glucose cotransporter-2 (SGLT2) inhibitors are known to be cardioprotective independent of glucose control, but the mechanisms of these benefits are unclear.
Dwight D. Harris, Sharif A. Sabe, Mark Broadwin, Christopher Stone, Cynthia Xu, Jiayu Hu, Meghamsh Kanuparthy, M. Ruhul Abid, Frank W. Sellke   +8 more
doaj   +1 more source

Ventriculo-arterial coupling for predicting cardiac index increase in infants after heart surgery. [PDF]

Interdiscip Cardiovasc Thorac Surg, 2023
Li W, Peng Y, Li Z, Huang J.
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Supine transfer test-induced changes in cardiac index predict fluid responsiveness in patients without intra-abdominal hypertension. [PDF]

BMC Anesthesiol, 2023
Zhao Z, Zhang Z, Liu J, Xia Z, Xing Q, Zhang Y, Zheng Y, Shen L, Lin Q, Gu D, Wang P, Zhang S, Li F, Zhu B.   +13 more
europepmc   +1 more source