Results 151 to 160 of about 6,309,608 (342)

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery.

Circulation, 1999
Thomas H. Lee, Edward R. Marcantonio, Carol M. Mangione, Eric J. Thomas, C. Polanczyk, E. Cook, D. Sugarbaker, Magruder C. Donaldson, R. Poss, Kalon K. L. Ho, L. Ludwig, Alex Pedan, L. Goldman   +12 more
semanticscholar   +1 more source

Cardiovascular Risk Factors from Early Life Predict Future Adult Cardiac Structural and Functional Abnormalities: A Systematic Review of the Published Literature

, 2014
Background: Clinical practice evaluates cardiovascular risk based on current risk factor (RF) levels [Blood pressure (BP), body mass index (BMI) and glycaemic control] largely disregarding previous risk-factor history over the totality of the life course.
Hughes, AD, Hardy, RJ, Mayet, J, Ghosh, AK, Chaturvedi, N, Kuh, D, Francis, DP   +6 more
core  

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Multimodal Soft Surgical Robots Enabled by Eco‐Degradable, Sterilizable Polymers and Transient Electronics

Advanced Functional Materials, EarlyView.
A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe, 
Minseong Chae, Kyung‐Sub Kim, Gyeong‐Seok Hwang, Jun‐Seok Shim, Sung‐Woo Kim, Yong‐Wu Kim, Jieun Han, Jae‐Young Bae, Jae‐Hwan Lee, Minjung Chae, Jooik Jeon, Joo‐Hyeon Park, You‐Jung Park, Ju‐Yong Lee, Sung‐Geun Choi, Min‐Ha Oh, Yong‐Joong Shin, Young‐In Ryu, Ji‐Woo Gu, Seong‐Yu Choi, Jeong‐Yun Sun, Jung Keun Hyun, Myoung‐Ryul Ok, Sang Yup Kim, Edyta Wyszkowska, Ju‐Young Kim, Kang‐Sik Lee, Seung‐Kyun Kang   +27 more
wiley   +1 more source

Proteomic Profiling of SGLT-2 Inhibitor Canagliflozin in a Swine Model of Chronic Myocardial Ischemia

Biomedicines
Background: Sodium–glucose cotransporter-2 (SGLT2) inhibitors are known to be cardioprotective independent of glucose control, but the mechanisms of these benefits are unclear.
Dwight D. Harris, Sharif A. Sabe, Mark Broadwin, Christopher Stone, Cynthia Xu, Jiayu Hu, Meghamsh Kanuparthy, M. Ruhul Abid, Frank W. Sellke   +8 more
doaj   +1 more source

Lower cardiac index levels relate to lower cerebral blood flow in older adults

Neurology, 2017
A. Jefferson, Dandan Liu, D. Gupta, Kimberly R. Pechman, J. Watchmaker, Elizabeth A. Gordon, S. Rane, Susan P. Bell, L. Mendes, L. Davis, K. Gifford, T. Hohman, Thomas J. Wang, M. Donahue   +13 more
semanticscholar   +1 more source

Frailty in Cardiac Surgery—Assessment Tools, Impact on Outcomes, and Optimisation Strategies: A Narrative Review

Background: Advancements in surgical care have made it possible to offer cardiac surgery to an older and frailer patient cohort. Frailty has been recognised as a prognostic indicator that impacts post-operative recovery and patient outcomes.
Jason M. Ali, Ashwini Chandiramani
core   +1 more source

Is body mass index before middle age related to coronary heart disease risk in later life?

, 2009
Objective: Although obesity beginning early in life is becoming more common, its implications for coronary heart disease (CHD) risk in later life remain uncertain.
Orfei, L, Osmond, C, Owen, C.G., Cook DG, Whincup, PH, Whincup, P.H., Rudnicka, A.R., Osmond C, A K Wathern, Chou, QA, Eriksson, JG, L Orfei, Eriksson, J.G., C Osmond, Kaye, SJ, D G Cook, Kaye, S.J., Wathern AK, C G Owen, Q-A Chou, Kaye SJ, J G Eriksson, Rudnicka, AR, Wathern, AK, A R Rudnicka, Rudnicka AR, Owen CG, Chou QA, Whincup PH, Eriksson JG, Wathern, A.K., Orfei L, S J Kaye, Cook, D.G., Chou, Q-A., Owen, CG, Cook, DG, P H Whincup, Osmond, C., Orfel, L.   +39 more
core   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source