Results 261 to 270 of about 1,144,205 (351)

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

Clinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan, Elizabeth Doolin, Dharam Paul, Julia Crossman, Michael Odontiadis, Philippe Danjou, Mark Smith, Spyros Papapetropoulos   +7 more
wiley   +1 more source

Cardiac Magnetic Resonance in Heart Failure: Diagnostic and Prognostic Assessments. [PDF]

J Cardiovasc Dev Dis
Pezzini S, Daus F, Galli G, Farina A, Fragasso G, Spoladore R.   +5 more
europepmc   +1 more source

Visible‐Light Photoswitchable Covalent Tetra‐Ortho‐Fluoro‐Azobenzene Carbon Nanodot Hybrids for Optostimulation

ChemPhotoChem, EarlyView.
Tetra‐ortho‐fluoroazobenzene hybrids bound to carbon nanodots (CNDs) are prepared by covalent amide coupling. These show reversible switching between trans and cis using visible light (448 nm/530 nm), while retaining emission. The hybrids are nontoxic to cells and enable optical stimulation and offering potential for advanced light‐controlled ...
Paul P. Debes, Dominic Schatz, Anthea Villano, Yagmur Aydogan‐Sun, Juan Pablo Martínez, Michal Langer, Janis Hessling, Monika Schönhoff, Bernd M. Smarsly, Silvio Osella, Josef Wachtveitl, Maria Rosa Antognazza, Giuseppe M. Paternò, Teresa Gatti, Hermann A. Wegner   +14 more
wiley   +1 more source

Comprehensive Assessment of Left Atrial Function: The Emerging Role of Cardiac Magnetic Resonance Feature Tracking. [PDF]

J Cardiovasc Dev Dis
Solsona-Caravaca J, Giustiniani A, Ródenas-Alesina E, Galian-Gay L, Oliveró R, Valente F, Casas G, Teixidó-Turà G, Vallejo N, Fernández-Galera R, González-Fernández V, Escribano-Escribano P, Hernández-Pineda A, Ferreira-González I, Rodríguez-Palomares JF.   +14 more
europepmc   +1 more source

Danon Disease: Diagnosis Made by Cardiac Magnetic Resonance

Sassan Hashemi, Hunter C. Wilson, Timothy C. Slesnick, Clayton Smith   +3 more
openalex   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

The Role of Cardiac Magnetic Resonance Imaging in the Management of Hypertrophic Cardiomyopathy. [PDF]

J Cardiovasc Dev Dis
Pugliese L, Luciano A, Chiocchi M.
europepmc   +1 more source

2D/3D CMR tissue tracking versus CMR tagging in the assessment of spontaneous T2DM rhesus monkeys with isolated diastolic dysfunction [PDF]

, 2018
et al,, Zheng, Jie
core   +1 more source

Patients With Undetermined Stroke Have Increased Atrial Fibrosis: A Cardiac Magnetic Resonance Imaging Study

Stroke, 2018
Ana Catarina Fonseca, P. Alves, N. Inácio, J. Marto, M. Viana-Baptista, Teresa Pinho-e-Melo, J. Ferro, A. Almeida   +7 more
semanticscholar   +1 more source

Prognostic role of high‐sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE‐CS

ESC Heart Failure, Volume 12, Issue 2, Page 869-878, April 2025.
Abstract Aims The prognostic role of high‐sensitivity cardiac troponin T (hs‐cTnT) as a biomarker in patients with cardiac sarcoidosis (CS) has yet to be fully determined, especially when compared with B‐type natriuretic peptide (BNP). Methods and Results In this post‐hoc analysis of the ILLUMINATE‐CS (ILLUstration of the Management and prognosIs of ...
Yuichi Baba, Toru Kubo, Takeru Nabeta, Yuya Matsue, Takeshi Kitai, Yoshihisa Naruse, Tatsunori Taniguchi, Hidekazu Tanaka, Takahiro Okumura, Kenji Yoshioka, Hiroaki Kitaoka   +10 more
wiley   +1 more source