Results 181 to 190 of about 168,609 (264)

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

Clinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan, Elizabeth Doolin, Dharam Paul, Julia Crossman, Michael Odontiadis, Philippe Danjou, Mark Smith, Spyros Papapetropoulos   +7 more
wiley   +1 more source

Diagnostic value of cardiac magnetic resonance imaging during transition care in adolescents with Turner syndrome. [PDF]

Front Pediatr
Więcek M, Olczak Z, Machnikowska-Sokołowska M, Błaszczyk E, Wójcik M, Mazur A, Starzyk J, Kusa J, Gawlik-Starzyk A.   +8 more
europepmc   +1 more source

Diagnostic Value of Right Ventricular Dysfunction in Tachycardia-Induced Cardiomyopathy Using Cardiac Magnetic Resonance Imaging

, 2016
Atsushi Okada, Ikutaro Nakajima, Yoshiaki Morita, Yuko Inoue, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Koji Miyamoto, Hideo Okamura, Satoshi Nagase, Takashi Noda, Takeshi Aiba, Shiro Kamakura, Toshihisa Anzai, Teruo Noguchi, Satoshi Yasuda, Kengo Kusano   +16 more
openalex   +2 more sources

Cardiovascular Risk of Romosozumab vs. Teriparatide: A Cohort Study Using Japan’s National Claims Database

Clinical Pharmacology &Therapeutics, EarlyView.
Disproportionality analyses suggested a cardiovascular risk signal for romosozumab, while statistically significant associations were not found in the real‐world database studies. Therefore, a larger comparative study was necessary to examine this signal.
Hotaka Maruyama, Eiko Iwasa, Shinya Watanabe, Tomoaki Hasegawa, Kazuhiro Kajiyama, Taihei Tanaka   +5 more
wiley   +1 more source

Retrospectively synchronized time-resolved ventricular cine images from 2D real-time exercise cardiac magnetic resonance imaging. [PDF]

Clin Physiol Funct Imaging
Åkesson J, Edlund J, Steding-Ehrenborg K, Heiberg E.   +3 more
europepmc   +1 more source

Visible‐Light Photoswitchable Covalent Tetra‐Ortho‐Fluoro‐Azobenzene Carbon Nanodot Hybrids for Optostimulation

ChemPhotoChem, EarlyView.
Tetra‐ortho‐fluoroazobenzene hybrids bound to carbon nanodots (CNDs) are prepared by covalent amide coupling. These show reversible switching between trans and cis using visible light (448 nm/530 nm), while retaining emission. The hybrids are nontoxic to cells and enable optical stimulation and offering potential for advanced light‐controlled ...
Paul P. Debes, Dominic Schatz, Anthea Villano, Yagmur Aydogan‐Sun, Juan Pablo Martínez, Michal Langer, Janis Hessling, Monika Schönhoff, Bernd M. Smarsly, Silvio Osella, Josef Wachtveitl, Maria Rosa Antognazza, Giuseppe M. Paternò, Teresa Gatti, Hermann A. Wegner   +14 more
wiley   +1 more source

Extreme phenotypes of the female athlete's heart: a sports-specific cardiac magnetic resonance imaging study. [PDF]

Eur Heart J Cardiovasc Imaging
van Hattum JC, van Diepen MA, Verwijs SM, Boekholdt SM, van Randen A, Groenink M, Planken RN, Moen MH, Daems JJN, Prakken NHJ, van de Sande DAJP, Velthuis BK, de Vries S, Walhout RJ, Pinto YM, Wilde AAM, Jørstad HT.   +16 more
europepmc   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Cardiac Magnetic Resonance Imaging in the Evaluation and Management of Scimitar Syndrome. [PDF]

Ann Thorac Surg Short Rep
Pettit AN, Mavroudis CD, Penney C, Gartenberg A, Fogel MA, Vaiyani D, Callahan R, Whitehead KK, Harris MA.   +8 more
europepmc   +1 more source

Prognostic role of high‐sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE‐CS

ESC Heart Failure, Volume 12, Issue 2, Page 869-878, April 2025.
Abstract Aims The prognostic role of high‐sensitivity cardiac troponin T (hs‐cTnT) as a biomarker in patients with cardiac sarcoidosis (CS) has yet to be fully determined, especially when compared with B‐type natriuretic peptide (BNP). Methods and Results In this post‐hoc analysis of the ILLUMINATE‐CS (ILLUstration of the Management and prognosIs of ...
Yuichi Baba, Toru Kubo, Takeru Nabeta, Yuya Matsue, Takeshi Kitai, Yoshihisa Naruse, Tatsunori Taniguchi, Hidekazu Tanaka, Takahiro Okumura, Kenji Yoshioka, Hiroaki Kitaoka   +10 more
wiley   +1 more source