Results 131 to 140 of about 910,276 (348)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Effect of Levosimendan on Low Cardiac Output Syndrome After Pericardiectomy

open access: yesTherapeutics and Clinical Risk Management
Likui Fang,1,2 Pengfei Zhu,2 Guocan Yu,2 Wang Lv,1 Jian Hu1 1Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, People’s Republic of China; 2Department of Thoracic Surgery, Hangzhou ...
Fang L, Zhu P, Yu G, Lv W, Hu J
doaj  

Há evidências favorecendo o uso de betabloqueadores e dobutamina na insuficiência cardíaca aguda? Is there evidence favoring the use of beta-blockers and dobutamine in acute heart failure?

open access: yesArquivos Brasileiros de Cardiologia, 2013
Diversos estudos relataram os benefícios dos betabloqueadores (BB) para pacientes com insuficiência cardíaca sistólica. No entanto, muitos pacientes hospitalizados em decorrência de insuficiência cardíaca aguda já estão usando os BB e requerem ...
Luiz Carlos Santana Passos   +3 more
doaj  

Smart Catheters for Diagnosis, Monitoring, and Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman   +12 more
wiley   +1 more source

Supervised Machine Learning Models Predicting Postoperative Low Cardiac Output Syndrome In Neonates

open access: yesCritical Care Explorations
OBJECTIVE:. To train and test supervised machine learning (ML) models to predict low cardiac output syndrome (LCOS) within the first 48 postoperative hours in neonates undergoing cardiothoracic surgery. DESIGN:. Retrospective observational study.
Orkun Baloglu, MD   +7 more
doaj   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

Automated quantification and evaluation of motion artifact on coronary CT angiography images [PDF]

open access: yes, 2018
Purpose This study developed and validated a Motion Artifact Quantification algorithm to automatically quantify the severity of motion artifacts on coronary computed tomography angiography (CCTA) images. The algorithm was then used to develop a Motion IQ
Baginski, Scott G.   +6 more
core   +1 more source

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour   +6 more
wiley   +1 more source

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.

open access: yesCochrane Database of Systematic Reviews, 2018
J. Schumann   +8 more
semanticscholar   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman   +7 more
wiley   +1 more source

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