Results 61 to 70 of about 910,276 (348)

Increased Metabolic Rate in X-linked Hypophosphatemic Mice [PDF]

open access: yes, 1986
Hyp mice are a model for human X-linked hypophosphatemia, the most common form of vitamin D-resistant rickets. It has previously been observed that Hyp mice have a greater food consumption per gram body weight than do normal mice.
Meyer, M. H.   +2 more
core   +1 more source

Cardiac output-guided haemodynamic therapy for patients undergoing major gastrointestinal surgery: OPTIMISE II randomised clinical trial

open access: yesBritish medical journal
Objectives To evaluate the clinical effectiveness and safety of a perioperative algorithm for cardiac output-guided haemodynamic therapy in patients undergoing major gastrointestinal surgery. Design Multicentre randomised controlled trial.
Mark Rupert Brennan Thomas Garima Neil Borislava Vladim Edwards Pearse Kahan Hamborg Priyadarshini MacDona   +461 more
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:Hepatic fibrosis progresses with right heart failure, and becomes cardiac cirrhosis in a severe case. Although its causal factor still remains unclear. Here we evaluated the progression of hepatic fibrosis using a pulmonary artery banding (PAB)
Yoshitaka Fujimoto   +12 more
doaj   +1 more source

The effects of repetitive electric cardiac stimulation in dogs with normal hearts, complete heart block and experimental cardiac arrest [PDF]

open access: yes, 1955
Direct cardiac stimulation was conducted in the open chest. In normal animals, auricular stimulation at frequencies faster than the spontaneous rate caused little change in vascular pressures or cardiac output.
GAERTNER, RA, STARZL, TE, WEBB, RC
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

The predictive value of plasma B-type natriuretic peptide levels on outcome in children with pulmonary hypertension undergoing congenital heart surgery

open access: yesRevista Brasileira de Anestesiologia, 2014
Background and objectives: In children undergoing congenital heart surgery, plasma brain natriuretic peptide levels may have a role in development of low cardiac output syndrome that is defined as a combination of clinical findings and interventions to ...
Ayse Baysal   +5 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Vasopressin in the pediatric cardiac intensive care unit: Myth or reality

open access: yesAnnals of Pediatric Cardiology, 2009
Pediatric cardiac surgery is undergoing a metamorphosis, with more and more critical patients being operated in our country today. Although the principles of physiology have not changed, it is imperative that care providers continue to stay abreast with ...
Singh Vishal   +3 more
doaj  

Poor agreement between cardiac output measurements from the pressure recording analytical method and pulmonary artery thermodilution in patients with low cardiac output: preliminary results from a prospective observational method comparison pilot study

open access: yesFrontiers in Anesthesiology
BackgroundContinuous hemodynamic monitoring is essential for guiding goal-directed therapy in high-risk cardiac surgery patients, particularly those prone to low-output syndrome.
Maximilian J. G. Oremek   +5 more
doaj   +1 more source

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