Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. [PDF]
The extracellular matrix is a master regulator of tissue homeostasis in health and disease. Here we examined how the small, leucine-rich, extracellular matrix proteoglycan decorin regulates cardiomyocyte metabolism during fasting in vivo.
Gubbiotti, Maria A.+4 more
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Preoperative and perioperative use of levosimendan in cardiac surgery: European expert opinion [PDF]
In cardiac surgery, postoperative low cardiac output has been shown to correlate with increased rates of organ failure and mortality. Catecholamines have been the standard therapy for many years, although they carry substantial risk for adverse cardiac ...
A., Eremenko+26 more
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This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey+5 more
wiley +1 more source
Relationship of blood pressure and flow during CPR to chest compression amplitude: Evidence for an effective compression threshold [PDF]
This study was conducted to investigate the importance of the depth of chest compression in producing effective cardiopulmonary resuscitation (CPR) in animals, as indicated by cardiac output and mean arterial blood pressure.
Babbs, Charles F+4 more
core +2 more sources
Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew+2 more
wiley +1 more source
A new approach to non-invasive oxygenated mixed venous PCO(sub)2 [PDF]
A clinically practical technique was developed to calculate mixed venous CO2 partial pressure for the calculation of cardiac output by the Fick technique.
Ansel, Clifford A., Fisher, Joseph A.
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Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions
Implantable devices significantly enhance healthcare but are limited by battery life. Ultrasound power transfer technology offers a promising solution for sustainable operation. This review addresses gaps in current research, particularly in sound field analysis and energy efficiency optimization.
Yi Zheng+6 more
wiley +1 more source
Comparison of two cardiac output monitors, qCO and LiDCO, during general anesthesia [PDF]
Background: Optimization of cardiac output (CO) has been evidenced to reduce postoperative complications and to expedite the recovery. Likewise, CO and other dynamic cardiac parameters can describe the systemic blood flow and tissue oxygenation state and
Escrivá, Jesús+6 more
core +1 more source
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu+4 more
wiley +1 more source
Starling curves and central venous pressure [PDF]
Recent studies challenge the utility of central venous pressure monitoring as a surrogate for cardiac preload. Starting with Starling’s original studies on the regulation of cardiac output, this review traces the history of the experiments that ...
Bakker, J. (Jan), Berlin, C. (Cheryl)
core +2 more sources