Results 131 to 140 of about 458,052 (360)

Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice‐Switching Oligonucleotides

Advanced Materials, EarlyView.
Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu, Hanna M. G. Barriga, Margaret N. Holme, Stefanie Morf, James J. Doutch, Samir EL Andaloussi, Tomas Kjellman, Markus Johnsson, Justas Barauskas, Molly M. Stevens   +9 more
wiley   +1 more source

Successful use of levosimendan as a primary inotrope in pediatric cardiac surgery: An observational study in 110 patients

Annals of Pediatric Cardiology, 2016
Context: Levosimendan is a new generation inotrope with calcium sensitizing properties and proven benefits in adults. Aims: This study investigates the use of levosimendan as a first line inotrope in congenital heart surgery.
Reena Khantwal Joshi, Neeraj Aggarwal, Mridul Aggarwal, Rakesh Pandey, Veronique Dinand, Raja Joshi   +5 more
doaj   +1 more source

High-output Cardiac Failure Caused by Large Coronary Artery Fistulas Treated with Coil Embolization [PDF]

There are many causes of high-output cardiac failure. We present a unique case of high-output cardiac failure caused by multiple coronary-to-pulmonary artery (PA) fistulas, which, to our knowledge, is a rare finding that has not been previously ...
Mustafa, Muhammad, Mustafa, Nawal, Nadeem, Hajra, Tafaesse, Blain   +3 more
core   +2 more sources

THE CENTRAL ACTION OF LIGNOCAINE AND ITS EFFECT ON CARDIAC OUTPUT [PDF]

, 1959
Frederick F. Kao, ULLA H. JALAR
openalex   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Correlation of carotid blood flow and corrected carotid flow time with invasive cardiac output measurements

Critical Ultrasound Journal, 2017
Background Non-invasive measures that can accurately estimate cardiac output may help identify volume-responsive patients. This study seeks to compare two non-invasive measures (corrected carotid flow time and carotid blood flow) and their correlations ...
Irene W. Y. Ma, Joshua D. Caplin, Aftab Azad, Christina Wilson, Michael A. Fifer, Aranya Bagchi, Andrew S. Liteplo, Vicki E. Noble   +7 more
doaj   +1 more source

Effect of hypokinesia on cardiac contractile function and nervous regulation of the heart [PDF]

Longterm hypokinesia caused cardiac deadaptation in rabbits, which resulted in the diminishing of the left ventricular rate of contraction and relaxation, joined later by decreased vascular resistance.
Gorina, M. S., Kapelko, V. I., Larinov, N. P., Meyerson, F. Z., Shchegolkov, A. N.   +4 more
core   +1 more source

Transforming Healthcare: Intelligent Wearable Sensors Empowered by Smart Materials and Artificial Intelligence

Advanced Materials, EarlyView.
Wearable sensors, empowered by AI and smart materials, revolutionize healthcare by enabling intelligent disease diagnosis, personalized therapy, and seamless health monitoring without disrupting daily life. This review explores cutting‐edge advancements in smart materials and AI‐driven technologies that empower wearable sensors for diagnostics and ...
Shuwen Chen, Shicheng Fan, Zheng Qiao, Zixiong Wu, Baobao Lin, Zhijie Li, Michael A. Riegler, Matthew Yu Heng Wong, Arve Opheim, Olga Korostynska, Kaare Magne Nielsen, Thomas Glott, Anne Catrine T. Martinsen, Vibeke H. Telle‐Hansen, Chwee Teck Lim   +14 more
wiley   +1 more source

CARDIAC OUTPUT DURING EXCITATION OF CHEMOREFLEXES IN THE CAT [PDF]

, 1958
Gwenda R. Barer, E Nusser
openalex   +1 more source

Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL

Advanced Materials Interfaces, EarlyView.
Brain movement significantly impacts the biocompatibility of neural probes due to continuous strain on neural tissue. This study examines strain profiles across various brain models and movement types, challenging the 5% damage threshold at the electrode–tissue interface.
Ali Sharbatian, Akhilesh Kamtikar, Danesh Ashouri Vajari, Thomas Stieglitz   +3 more
wiley   +1 more source