This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang+11 more
wiley +1 more source
Machine learning-enabled estimation of cardiac output from peripheral waveforms is independent of blood pressure measurement location in an in silico population. [PDF]
Aslanidou L+5 more
europepmc +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Effect of Levosimendan on Low Cardiac Output Syndrome After Pericardiectomy. [PDF]
Fang L, Zhu P, Yu G, Lv W, Hu J.
europepmc +1 more source
Study on Congestive Heart Failure by Ballistocardiogram (1) : CARDIAC OUTPUT STROKE-VOLUME
Susumu Yorifuji
openalex +2 more sources
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan+13 more
wiley +1 more source
Standardization and quality control of the introduction of a noninvasive cardiac output monitor for pregnancy measurements in a low- and middle-income country. [PDF]
Perry H+10 more
europepmc +1 more source
Measurement of Cardiac Output by an Indicator-Dilution Method [PDF]
Richard A. Theye+3 more
openalex +1 more source
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv+11 more
wiley +1 more source
Correlation of end-tidal carbon dioxide with transthoracic echocardiography derived cardiac output for the assessment of fluid responsiveness: A prospective observational study. [PDF]
Raj SK+3 more
europepmc +1 more source