Results 231 to 240 of about 451,923 (312)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Organic Bulk‐Heterojunction‐Integrated Flexible Perovskite Photodetection Arrays for High‐Speed Broadband Optical Communication

open access: yesAdvanced Science, EarlyView.
A flexible broadband photodetector is realized by integrating a perovskite with an organic bulk‐heterojunction. It achieves high external quantum efficiency (EQE) (>80% visible, >60% near‐infrared (NIR)), ultralow dark current, and fast response, enabling self‐powered, high‐detectivity operation.
Xin Hong   +9 more
wiley   +1 more source

Prevention of spinal anaesthesia-induced hypotension during caesarean section using noninvasive cardiac output monitoring: A randomised clinical trial. [PDF]

open access: yesEur J Anaesthesiol Intensive Care
Higashi M   +7 more
europepmc   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

open access: yesAdvanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha   +11 more
wiley   +1 more source

Advances in noninvasive cardiac output monitoring.

open access: yesAnnals of Cardiac Anaesthesia, 2002
Linton David, Gilon D
doaj  

Paradoxic septal motion during PEEP ventilation [PDF]

open access: yes, 1989
Daum, S.   +5 more
core   +1 more source

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