Results 251 to 260 of about 451,923 (312)

Fourth Generation FloTrac Software Pulse Contour Analysis for Measuring and Trending Cardiac Output: A Method Comparison Study. [PDF]

Acta Anaesthesiol Scand
Dinesen C, Vistisen ST, Aagaard R, Bisgaard SS, Juhl-Olsen P.   +4 more
europepmc   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

Effects of pulse indicated continuous cardiac output monitoring on outcomes of intensive care unit patients with shock: a propensity score matching analysis. [PDF]

World J Emerg Med
Li D, Xia Y, Hu Y, Du L, Huang T, Chen C, Xiao Y, Li L, Yu Y, Dai S, Cui W, Shen H.   +11 more
europepmc   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Effect of Levosimendan on Low Cardiac Output Syndrome After Pericardiectomy. [PDF]

Ther Clin Risk Manag
Fang L, Zhu P, Yu G, Lv W, Hu J.
europepmc   +1 more source

A Two Parameters for the Evaluation of Hypovolemia in Patients with Septic Shock: Inferior Vena Cava Collapsibility Index (IVCCI), Delta Cardiac Output

, 2019
Cem Kıvılcım Kaçar, Osman Uzundere, Abdülkadir Yektaş   +2 more
openalex   +2 more sources

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Machine learning-enabled estimation of cardiac output from peripheral waveforms is independent of blood pressure measurement location in an in silico population. [PDF]

Sci Rep
Aslanidou L, Rovas G, Mohammadi R, Anagnostopoulos S, Çelikbudak Orhon C, Stergiopulos N.   +5 more
europepmc   +1 more source

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

Advanced Science, EarlyView.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme, Rocio K. Finol‐Urdaneta, Jeffrey R. McArthur, Nicholas R. Marzano, Simon Maksour, Amarinder Thind, Yang Guo, Dominic Kaul, Marnie Maddock, Oliver Friedrich, Boris Martinac, David J. Adams, Mirella Dottori   +12 more
wiley   +1 more source

Standardization and quality control of the introduction of a noninvasive cardiac output monitor for pregnancy measurements in a low- and middle-income country. [PDF]

Acta Obstet Gynecol Scand
Perry H, Tusiimirwe E, Nakayenga A, Ganzevoort W, Tumuhamye J, Nakato W, Byamugisha J, Mbote K, Papageorghiou AT, Ali S, iTECH Consortium Members.   +10 more
europepmc   +1 more source