Robust neuromorphic coupled oscillators for adaptive pacemakers [PDF]
Sci Rep 11, 18073 (2021), 2021 Neural coupled oscillators are a useful building block in numerous models and applications. They were analyzed extensively in theoretical studies and more recently, in biologically realistic simulations of spiking neural networks. The advent of mixed-signal analog/digital neuromorphic electronic circuits provides new means for implementing neural ...
arxiv +1 more source
Impact of chronic fetal hypoxia and inflammation on cardiac pacemaker cell development [PDF]
Cells 9(3), 733, 2020, 2020 Chronic fetal hypoxia and infection are examples of adverse conditions during complicated pregnancy, which impact cardiac myogenesis and increase the lifetime risk of heart disease. However, the effects that chronic hypoxic or inflammatory environments exert on cardiac pacemaker cells are poorly understood.
arxiv +1 more source
Improved Cardiac Arrhythmia Prediction Based on Heart Rate Variability Analysis [PDF]
, 2022 Many types of ventricular and atrial cardiac arrhythmias have been discovered in clinical practice in the past 100 years, and these arrhythmias are a major contributor to sudden cardiac death. Ventricular tachycardia, ventricular fibrillation, and paroxysmal atrial fibrillation are the most commonly-occurring and dangerous arrhythmias, therefore early ...
arxiv +1 more source
ASIC Implementation of Denoising Filters for Pacemakers [PDF]
arXiv, 2023 Cardiac Pacemakers are used to regulate the hearts rhythm and prevent abnormal heart beats. Patients undergo a minimal surgery to get the pacemaker implanted in the body, whereas these devices do have their limitations such as battery life, power consumption and integrated circuit area which makes it difficult for elderly and children to undergo this ...
arxiv
Physiological accuracy in simulating refractory cardiac tissue: the volume-averaged bidomain model vs. the cell-based EMI model [PDF]
arXiv, 2023 The refractory period of cardiac tissue can be quantitatively described using strength-interval (SI) curves. The information captured in SI curves is pertinent to the design of anti-arrhythmic devices including pacemakers and implantable cardioverter defibrillators.
arxiv
Multimodal Foundation Models For Echocardiogram Interpretation [PDF]
arXiv, 2023 Multimodal deep learning foundation models can learn the relationship between images and text. In the context of medical imaging, mapping images to language concepts reflects the clinical task of diagnostic image interpretation, however current general-purpose foundation models do not perform well in this context because their training corpus have ...
arxiv
Multiple mechanisms of spiral wave breakup in a model of cardiac electrical activity [PDF]
, 2002 It has become widely accepted that the most dangerous cardiac arrhythmias are due to re- entrant waves, i.e., electrical wave(s) that re-circulate repeatedly throughout the tissue at a higher frequency than the waves produced by the heart's natural pacemaker (sinoatrial node). However, the complicated structure of cardiac tissue, as well as the complex
arxiv +1 more source
Synchronization of the cardiac pacemaker model with delayed pulse-coupling [PDF]
arXiv, 2011 We consider the integrate-and-fire model of the cardiac pacemaker with delayed pulsatile coupling. Sufficient conditions of synchronization are obtained for identical and non-identical oscillators.
arxiv
Computer Algorithms for Automated Detection and Analysis of Local Ca2+ Releases in Spontaneously Beating Cardiac Pacemaker Cells [PDF]
, 2017 Local Ca Releases (LCRs) are crucial events involved in cardiac pacemaker cell function. However, specific algorithms for automatic LCR detection and analysis have not been developed in live, spontaneously beating pacemaker cells. Here we measured LCRs using a high-speed 2D-camera in spontaneously contracting sinoatrial (SA) node cells isolated from ...
arxiv +1 more source
Towards the Emulation of the Cardiac Conduction System for Pacemaker Testing [PDF]
arXiv, 2016 The heart is a vital organ that relies on the orchestrated propagation of electrical stimuli to coordinate each heart beat. Abnormalities in the heart's electrical behaviour can be managed with a cardiac pacemaker. Recently, the closed-loop testing of pacemakers with an emulation (real-time simulation) of the heart has been proposed.
arxiv