Results 271 to 280 of about 115,833 (340)

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

open access: yesExperimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti   +6 more
wiley   +1 more source

Atrial fibrillation, sinoatrial and atrioventricular node dysfunction in a mouse model of heart failure with preserved ejection fraction

open access: yesExperimental Physiology, EarlyView.
Summary of the timeline of characterized events related to atrial fibrilation (AF) and diastolic dysfunction in a mouse heart failure with preserved ejection fraction (HFpEF) model. Three weeks after the initiation of the diet regimen with high fat diet (HFD) and Nω‐nitro‐l‐arginine methyl ester (l‐NAME) in drinking water to induce HFpEF, significantly
Bernadin Ndongson‐Dongmo   +2 more
wiley   +1 more source

Computational study of the excitation of human induced pluripotent stem cell‐derived cardiomyocytes

open access: yesExperimental Physiology, EarlyView.
Abstract Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs) have proven to be a revolutionary advance for tissue engineering, disease modelling, and drug testing and discovery. Computational modelling enables detailed electrophysiological analysis that is otherwise difficult or impossible to achieve under strictly experimental ...
Roshni Shetty   +2 more
wiley   +1 more source

Frequency responses of human magnetophosphene perception thresholds during dark adaptation point to rod modulation

open access: yesExperimental Physiology, EarlyView.
Abstract Magnetophosphenes are flickering lights perceived when an extremely low frequency magnetic field generates a sufficiently strong electric field in the head. Understanding how phosphenes are produced is crucial, as they form the basis for international safety standards and guidelines for both workers and the general population.
Nicolas Bouisset   +4 more
wiley   +1 more source

A Case with Deep Brain Stimulation and Cardiac Pacemaker

open access: hybrid
Dilek İşçan   +3 more
openalex   +2 more sources

Differential contribution of T‐type voltage‐gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits

open access: yesExperimental Physiology, EarlyView.
Abstract figure T‐type VGCCs contribute to the contraction of the rabbit aorta and modulate both contraction and vasodilation in the rabbit renal artery. α1, alpha 1 adrenergic receptor; ATR, angiotensin II receptor; Ang II, angiotensin II; CaM, calmodulin; Cav3, T‐type voltage‐gated Ca2⁺ channels; cGMP, cyclic guanidine monophosphate; EC, endothelial ...
Andrea Suarez   +6 more
wiley   +1 more source

Quantifying skin microvascular function responses to distinct forms of heat stress in humans using optical coherence tomography

open access: yesExperimental Physiology, EarlyView.
Abstract Optical coherence tomography (OCT) enables visualization and quantification of the cutaneous microvasculature, yet no study has compared responses to distinct forms of heating in humans. We hypothesized that local skin heating (LH) would evoke larger responses in microvascular diameter, velocity, flow and density than passive whole‐body ...
Kristanti W. Wigati   +5 more
wiley   +1 more source

An update on pacemaking in the myometrium

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya   +2 more
wiley   +1 more source

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