Results 101 to 110 of about 1,826,857 (351)

Citrus aurantium honey‐mediated gut homeostasis and anti‐inflammation via Thorl/Nprl2‐TORC1 signaling: Network pharmacology and Drosophila validation

Animal Models and Experimental Medicine, EarlyView.
The study employed a four‐tiered strategy: (1) UHPLC‐FTMS profiling of Citrus aurantium honey to characterize its chemical composition; (2) network pharmacology analysis integrating target prediction, protein–protein interaction networks, and KEGG pathway enrichment to identify the Thor1/Nprl2‐TORC1 axis as a key mechanistic pathway; (3) in vitro ...
Wenqi Wan, Ruiguang Huang, Shuqiong Cao, Luxia Pan, Wenkai Zhang, Wujun Jiang, Zhiyong Liu   +6 more
wiley   +1 more source

The Apparent and the Effective PR Interval, Insights for Cardiac Pacing

, 2011
A 75-year-old-male patient with dual chamber pacemaker presented with a bizarre EKG showing a unique spike within the QRS complex. Apparent PR interval was 160 ms and effective atrio- right ventricular delay was 210 ms due to right bundle branch block ...
Antoine Kossaify
core   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source

Personal HealthCare of Things: A novel paradigm and futuristic approach

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract This study provides an investigative approach and offers a complete review of research on Internet of Medical Things (IoMT), describing the progress in general and highlighting the research issues, trends, and future aspects of IoMT. Exploring a research strategy for IoMT systems is vital as the need for IoT in healthcare grows. By aggregating
Surbhi Gupta, Mohammad Shabaz, Ankur Gupta, Abdullah Alqahtani, Shtwai Alsubai, Isaac Ofori   +5 more
wiley   +1 more source

DNA methylation-based telomere length is more strongly associated with cardiovascular disease and long-term mortality than quantitative polymerase chain reaction-based telomere length: evidence from the NHANES 1999–2002

Clinical Epigenetics
Background Telomere length (TL) serves as a pivotal gauge of cellular aging, with shorter TL linked to various age-related ailments. Recently, a DNA methylation-based TL estimator, known as DNAmTL, has emerged as a novel TL measurement tool.
Qianhui Wang, Yuanfeng Gao, Jie Song, Dilare Taiwaikuli, Huanhuan Ding, Xinchun Yang, Baopeng Tang, Xianhui Zhou   +7 more
doaj   +1 more source

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA).

Revista Española de Cardiología, 2022
M. Glikson, J. Nielsen, M. Kronborg, Y. Michowitz, A. Auricchio, I. Barbash, J. Barrabés, G. Boriani, F. Braunschweig, M. Brignole, H. Burri, A. Coats, J. Deharo, V. Delgado, G. Diller, C. Israel, A. Keren, R. Knops, D. Kotecha, C. Leclercq, B. Merkely, C. Starck, I. Thylén, J. Tolosana   +23 more
semanticscholar   +1 more source

Techniques for Identification of Left Ventricular Asynchrony for Cardiac Resynchronization Therapy in Heart Failure

, 2005
The most recent treatment option of medically refractory heart failure includes cardiac resynchronization therapy (CRT) by biventricular pacing in selected patients in NYHA functional class III or IV heart failure. The widely used marker to indicate left
Peter, Schuster, Svein, Faerestrand
core  

A study of electrode-tissue impedances encountered in cardiac pacing [PDF]

, 1987
Any study of the electrical properties of electrodeelectrolyte systems is rendered difficult by their dependance on, amongst other things, electrode history, electrode surface finish, electrode geometry, electrode area, electrolyte composition and the
McAdams, Eric Thomas
core  

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Single-chamber Versus Dual-chamber Implantable Cardioverter Defibrillators: Do We Need Physiologic Pacing in The Course?

, 2006
Background: Many patients with ICD receive different antiarrhythmic drugs (e.g. sotalol, amiodarone, β-blockers) because of ventricular or atrial tachycardias.
Buck, Thomas, Marco Budeus, Stefan Sack, Erbel, Raimund, Budeus, Marco, Wieneke, Heinrich, Sack, Stefan, Raimund Erbel, Thomas Buck, Heinrich Wieneke   +9 more
core