Results 281 to 290 of about 1,642,043 (400)

Caloric Restriction Reprograms Adipose Tissues in Rhesus Monkeys

open access: yesAging Cell, EarlyView.
Here we show shared and depot‐specific adaptations to life‐long CR in subcutaneous and visceral adipose depots from advanced‐age male rhesus monkeys. Transcriptomics reveal differences between the depots, as well as shared and distinct CR‐responsive pathways.
Josef P. Clark   +6 more
wiley   +1 more source

Quantitative Evaluation of a Directly Depolarized Area Induced by High-Output Pacing on the Cardiac Muscle

open access: bronze, 2000
Masahiko Moriguchi   +6 more
openalex   +2 more sources

The m6A Demethylase Fto Enhances Susceptibility to Atrial Fibrillation by Demethylating Kcne1 in Aging Mice

open access: yesAging Cell, EarlyView.
Aging‐induced accumulation of PGE2 in cardiomyocytes blocks the degradation of Fto. Elevation of Fto in the atria represses m6A methylation of Kcnel which, in turn, leads to the reduction of Kcnel mRNA and protein. Reduced Kcnel enhances IKs currents and thereby shortens APD in atrial cardiomyocytes and increases AF inducibility.
Ruopeng Tan   +8 more
wiley   +1 more source

Psychological Comorbidity in Patients Presenting to the Emergency Department With Low‐Risk Chest Pain and Anxiety

open access: yesAcademic Emergency Medicine, EarlyView.
ABSTRACT Objective Low‐risk chest pain (LRCP) is one of the most common conditions presenting in the emergency department (ED) and is strongly associated with anxiety. The purpose of this study is to determine the prevalence of other psychological comorbidities and clinical factors associated with severe anxiety in LRCP.
Linh Dang   +9 more
wiley   +1 more source

Development of a Novel Frailty Trigger for Use at Triage in the Emergency Department

open access: yesAcademic Emergency Medicine, EarlyView.
ABSTRACT Background Emergency Department (ED) Triage identifies patients with urgent needs. Frailty is not routinely identified and older patients presenting atypically may be inappropriately triaged as low priority. The introduction of a frailty modifier at triage is recommended in international guidelines, but is not yet widely‐adopted.
Elizabeth Moloney   +6 more
wiley   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

open access: yesAndrology, EarlyView.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani   +6 more
wiley   +1 more source

Differences and Commonalities of Electrical Stimulation Paradigms After Central Paralysis and Amputation

open access: yesArtificial Organs, EarlyView.
Invasive and non‐invasive functional electrical stimulation (FES) is a well‐established method to partially restore function after paralysis and deliver sensory feedback after amputation. This work summarizes the current state‐of‐the‐art of FES for restoring function, supporting rehabilitation therapy, and assistive devices.
Thomas Stieglitz   +3 more
wiley   +1 more source

Ultra-High-Frequency ECG in Cardiac Pacing and Cardiac Resynchronization Therapy: From Technical Concept to Clinical Application. [PDF]

open access: yesJ Cardiovasc Dev Dis
Nguyên UC   +11 more
europepmc   +1 more source

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