Results 41 to 50 of about 8,969 (219)

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

open access: yesAdvanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon   +6 more
wiley   +1 more source

Reversible third-degree atrioventricular block in a Poodle-Toy with degenerative mitral valve disease and pyometra

open access: yesBrazilian Journal of Veterinary Medicine, 2021
Third degree atrioventricular block is a severe arrhythmia, being the most common   indication for artificial cardiac pacing in dogs. Spontaneous reversion to normal sinus rhythm is very rare or exceptional.
Gustavo Luiz Gouvêa Almeida   +4 more
doaj   +1 more source

Perceived Time Shapes Physical Fatigue Accumulation and Its Neural Oscillatory Correlates

open access: yesAdvanced Science, EarlyView.
Can a clock change the course of physical fatigue? By covertly manipulating the clock calibration during repeated isometric contractions, we showed that perceived time shapes fatigue accumulation and frontal oscillatory dynamics. While fatigue accumulation was only reduced when the clock was slowed down, frontal oscillatory dynamics followed perceived ...
Pierre‐Marie Matta   +3 more
wiley   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

Precision-guided heart failure interventions: The expanding role of advanced cardiac imaging and artificial intelligence

open access: yesAmerican Heart Journal Plus
Heart failure remains a major driver of hospitalization, morbidity, impaired quality of life, and healthcare expenditure. As disease phenotypes become more diverse and therapeutic options expand beyond pharmacological treatment alone, contemporary heart ...
Arif Albulushi, Hatem Al-Farhan
doaj   +1 more source

Short‐time ventricular tachycardia ablation for cardiac sarcoidosis using coherent map

open access: yesJournal of Arrhythmia, 2022
A 69‐year‐old woman with isolated cardiac sarcoidosis was hospitalized for frequent appropriate implantable converter defibrillator therapies for ventricular tachycardia (VT) despite of favorably controlled condition with oral prednisolone.
Takashi Hiruma   +4 more
doaj   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

open access: yesAdvanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Conduction System Pacing for Heart Failure [PDF]

open access: yesTexas Heart Institute Journal
None.
Nathan R. Smith, MD   +2 more
doaj   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

open access: yesAdvanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu   +3 more
wiley   +1 more source

Case Report Endovascular single-chamber pacemaker implantation using active fixation in a 8 years old Dogue de Bordeaux with presumed Persistent Atrial Standstill: the first case documented in Romania

open access: yesCluj Veterinary Journal
Background: Symptomatic bradyarrhythmias in dogs can lead to sever hemodynamical compromise due to impaired oxygen and nutrients delivery and even sudden cardiac death.
Florin Leca   +8 more
doaj   +1 more source

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