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Predictive value of left atrial remodeling for response to cardiac resynchronization therapy
Response to cardiac resynchronization therapy varies significantly among patients, with one third of them failing to demonstrate left ventricular reverse remodeling after cardiac resynchronization therapy.
Bouwmeester Sjoerd+4 more
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GRAPHICAL ABSTRACTCIED, cardiac implantable electronic devices; CRT, cardiac resynchronization therapy; CRT-D, cardiac resynchronization therapy defibrillator; EA, electroanatomical; ICD, implantable cardioverter defibrillator; LBB, left bundle branch ...
Mate Vamos+4 more
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Ischemic Etiology and Clinical Outcomes Following Cardiac Resynchronization Therapy
Optimal patient selection for cardiac resynchronization therapy is crucial. There are several concerns that allow to better clarify the association between the ischemic etiology of heart failure and the response to cardiac resynchronization therapy.
Teruhiko Imamura
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Overview of Current Strategies Aiming at Improving Response to Cardiac Resynchronization Therapy
Cardiac resynchronization therapy is a treatment modality developed in the early 2000s that targets the mechanical and electrical dyssynchrony in heart failure with reduced ejection fraction patients. Appropriate patient selection conditions specified in
Yakup Yunus Yamantürk+3 more
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A fast computational model for the electrophysiology of the whole human heart [PDF]
In this study we present a novel computational model for unprecedented simulations of the whole cardiac electrophysiology. According to the heterogeneous electrophysiologic properties of the heart, the whole cardiac geometry is decomposed into a set of coupled conductive media having different topology and electrical conductivities: (i) a network of ...
arxiv +1 more source
A new method using deep learning to predict the response to cardiac resynchronization therapy [PDF]
Background. Clinical parameters measured from gated single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) have value in predicting cardiac resynchronization therapy (CRT) patient outcomes, but still show limitations. The purpose of this study is to combine clinical variables, features from electrocardiogram (ECG), and ...
arxiv +1 more source
A new method using machine learning to integrate ECG and gated SPECT MPI for Cardiac Resynchronization Therapy Decision Support on behalf of the VISION-CRT [PDF]
Cardiac resynchronization therapy (CRT) has been established as an important therapy for heart failure. Mechanical dyssynchrony has the potential to predict responders to CRT. The aim of this study was to report the development and the validation of machine learning (ML) models which integrates ECG, gated SPECT MPI (GMPS) and clinical variables to ...
arxiv +1 more source
GEASI: Geodesic-based Earliest Activation Sites Identification in cardiac models [PDF]
The identification of the initial ventricular activation sequence is a critical step for the correct personalization of patient-specific cardiac models. In healthy conditions, the Purkinje network is the main source of the electrical activation, but under pathological conditions the so-called earliest activation sites (EASs) are possibly sparser and ...
arxiv +1 more source
Background: Cardiovascular disease remains the leading cause of death in the European Union and worldwide. Constant improvement in cardiac care is leading to an increased number of patients with heart failure, which is a challenging condition in terms of
Bartosz Krzowski+7 more
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Background Cardiac resynchronization therapy has been shown to benefit selected patients with heart failure and reduced ejection fraction. Older patients have been underrepresented in randomized trials.
Laure Champ-Rigot+6 more
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