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Cardiac resynchronization therapy
Current Cardiology Reports, 2002Despite advances in medical therapy for patients with congestive heart failure, morbidity and mortality remain high. Conventional atrioventricular pacing with a short atrioventricular delay was first introduced as a nonpharmacologic treatment for patients with severe heart failure.
Silke Isabelle, Trautmann +2 more
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Cardiac Resynchronization Therapy
JACC: Clinical Electrophysiology, 2022Abstract This chapter examines cardiac resynchronization therapy (CRT), or biventricular pacing (BVP), which is now well established as a therapeutic option for selected, symptomatic patients with heart failure due to left ventricular systolic dysfunction and reduced ejection fraction (HFrEF) and a prolonged QRS interval.
Varun Sundaram, Judith A. Mackall
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Cardiac resynchronization therapy
Current Treatment Options in Cardiovascular Medicine, 2008It is now well established that electrical and mechanical dyssynchrony are not clinically synonymous; however, at present no individual noninvasive method can reliably and consistently identify the criteria for mechanical dysfunction correctable through device therapy. The results of the PROSPECT (Predictors of Response to CRT) trial not only highlight
Daniel M, Couri, Sunil, Mankad
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Cardiac Resynchronization Therapy
Progress in Cardiovascular Diseases, 2006Left ventricular (LV) dysynchrony, generally defined as the effect of intraventricular conduction defects or bundle branch block to produce nonsynchronous ventricular activation, places the failing heart at a further mechanical disadvantage. The deleterious effects of ventricular dysynchrony include suboptimal ventricular filling, paradoxical septal ...
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Cardiac resynchronization therapy in cardiomyopathies
Journal of Cardiovascular Medicine, 2014Cardiomyopathies are a heterogeneous group of diseases of the myocardium that represent a major cause of morbidity and mortality due to progressive heart failure or sudden death. Cardiac resynchronization therapy has become an essential therapeutic tool in the treatment of heart failure patients today.
Masarone D +8 more
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On the Underutilization of Cardiac Resynchronization Therapy
Journal of Cardiac Failure, 2014Cardiac resynchronization therapy (CRT) is an exciting therapy that can treat patients with systolic heart failure and left ventricular dysfunction who have a wide QRS complex. Indications for its use have been refined and expanded based on recent clinical data and guidelines, yet the rate of new CRT implants in the United States has not changed much ...
Alan J. Bank +2 more
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Indications for Cardiac Resynchronization Therapy
Cardiology Clinics, 2014Initial studies established patient selection criteria for cardiac resynchronization therapy (CRT) as left ventricular ejection fraction less than or equal to 35%, QRS greater than or equal to 120 ms, and New York Heart Association 3-4. Based on newer data, post hoc analyses, and meta-analyses, these criteria have been refined and guidelines updated ...
Thomas M, O'Brien +2 more
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Cardiac Resynchronization Pacing Therapy
Cardiology, 2004Approximately one third of patients with congestive heart failure and systolic dysfunction have an intraventricular conduction delay that is manifested as a QRS duration >120 ms. An intraventricular conduction delay adversely affects ventricular performance by causing dyssynchrony in ventricular activation.
Cash, Casey, Bradley P, Knight
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Optimization of Cardiac Resynchronization Therapy
Echocardiography, 2008Cardiac resynchronization is now an accepted and widespread therapy for patients with left ventricular (LV) systolic dysfunction. However, there are still a significant number of patients that do not appear to gain benefit, and this is currently the focus of a great deal of research.
Amit, Bhan +2 more
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Future of Cardiac Resynchronization Therapy
Future Cardiology, 2008Cardiac resynchronization therapy (CRT) has proven to be a beneficial treatment option in patients with severe drug refractory heart failure in the presence of electromechanical dyssynchrony. More recent trials have demonstrated mortality benefits associated with CRT, and even further reductions when combined with an internal cardiac defibrillator ...
Aruna Vishnu, Arujuna +2 more
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