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Challenges of cardiac sarcoidosis

Frontiers in Medicine, 2023
Sarcoidosis is a multisystem granulomatosis of unknown origin, which can involve almost any organ. Most frequently the disease involves the lungs and mediastinal lymph nodes, but it can affect the skin, the eyes, nervous system, the heart, kidneys ...
Irina R. Strambu, Irina R. Strambu
doaj   +3 more sources

A Challenging Case of Advanced Cardiac Sarcoidosis Refractory to Infliximab Therapy [PDF]

Clinical Case Reports
Cardiac sarcoidosis can be life‐threatening, and lack of response to immunosuppressive therapy remains a significant challenge in active disease. We present a case of refractory cardiac sarcoidosis despite third‐line immunosuppression (infliximab ...
Manal Ibrahim, Mansimran Singh Dulay, Kshama Wechalekar, Vasileios Kouranos, Rakesh Sharma   +4 more
doaj   +2 more sources

Isolated cardiac sarcoidosis: A systematic review [PDF]

Journal of International Medical Research
Background Isolated cardiac sarcoidosis is a distinct entity of sarcoidosis characterized by disease confined exclusively to the heart, without involvement of other organs.
Shokoufeh Hajsadeghi, Elham Piryaie, Shayan Mirshafiee   +2 more
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The Role of Echocardiography in the Contemporary Diagnosis and Prognosis of Cardiac Sarcoidosis: A Comprehensive Review

Life, 2023
Cardiac sarcoidosis (CS) is a rare inflammatory disorder characterised by the presence of non-caseating granulomas within the myocardium. Contemporary studies have revealed that 25–30% of patients with systemic sarcoidosis have cardiac involvement, with ...
Joseph Okafor, Rajdeep Khattar, Rakesh Sharma, Vasilis Kouranos   +3 more
doaj   +1 more source

Underdiagnosis of cardiac sarcoidosis by ECG and echocardiography in cases of extracardiac sarcoidosis

ERJ Open Research, 2022
Background Although screening with 12-lead electrocardiography and transthoracic echocardiography for cardiac involvement has been recommended for patients with biopsy-proven extracardiac sarcoidosis, cardiac sarcoidosis has been reported even in ...
Hiroshi Ohira, Takahiro Sato, Osamu Manabe, Noriko Oyama-Manabe, Akiko Hayashishita, Toshitaka Nakaya, Junichi Nakamura, Naoko Suzuki, Ayako Sugimoto, Sho Furuya, Satonori Tsuneta, Taku Watanabe, Ichizo Tsujino, Satoshi Konno   +13 more
doaj   +1 more source

Indirect pathological indicators for cardiac sarcoidosis on endomyocardial biopsy [PDF]

Journal of Pathology and Translational Medicine, 2020
Background The definitive pathologic diagnosis of cardiac sarcoidosis requires observation of a granuloma in the myocardial tissue. It is common, however, to receive a “negative” report for a clinically probable case. We would like to advise pathologists
Myung-Jin Cha, Jeong-Wook Seo, Seil Oh, Eun-Ah Park, Sang-Han Lee, Moon Young Kim, Jae-Young Park   +6 more
doaj   +1 more source

Features and clinical impact of extra-cardiac lesions with 18F-fluorodeoxyglucose positron emission tomography in patients with suspected cardiac sarcoidosis

International Journal of Cardiology: Heart & Vasculature, 2020
Background: Sarcoidosis is a systemic inflammatory disorder and can often affect any other organs beyond the heart. Whole-body 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is used to detect not only cardiac but also extra-cardiac ...
Haruhiko Higashi, Shinji Inaba, Chiharuko Iio, Katsuji Inoue, Akiyoshi Ogimoto, Masao Miyagawa, Teruhito Mochizuki, Shuntaro Ikeda, Osamu Yamaguchi   +8 more
doaj   +1 more source

High-risk and low prevalence disease: Cardiac sarcoidosis and some of its mimics

International Journal of Cardiology: Heart & Vasculature, 2023
In this narrative review of cardiac sarcoidosis, based on a literature search using the terms “cardiac sarcoidosis”, “tuberculous myocarditis”, “Whipple’s disease and myocarditis”, and”idiopathic giant cell myocarditis”, I have defined cardiac ...
Oscar M.P. Jolobe
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Challenges in diagnosing cardiac sarcoidosis: should we increase our index of suspicion?

Journal of Community Hospital Internal Medicine Perspectives, 2020
Sarcoidosis is a multisystem disease involving the lungs in up to 90% of cases; however, 30% of patients will have systemic sarcoidosis, including involvement of the heart. Cardiac sarcoidosis can affect any part of the heart and manifest in various ways,
Ariana Rose Tagliaferri
doaj   +1 more source

Adalimumab in the treatment of cardiac sarcoidosis: Single center case series and narrative literature review

Respiratory Medicine Case Reports, 2022
Background: Tumor necrosis factor (TNF) inhibitors have been used in the treatment of cardiac sarcoidosis, infliximab being the most commonly used.
Jaleel Jerry G. Sweis, Nabil William G. Sweis, Christian Ascoli, Benjamin Levin, Boaz Avitall, Israel Rubinstein, George Kondos, Daniel A. Culver, Marc Judson, Robert Baughman, Dawood Darbar, Wonder Drake, Shiva Shahrara, Leslie T. Cooper, Jr., Nadera J. Sweiss   +14 more
doaj   +1 more source