Results 221 to 230 of about 489,113 (345)
Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC)
Epilepsia, EarlyView.Abstract Objective
This randomized, double‐blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs).Dennis J. Dlugos, Ingrid E. Scheffer, Jacqueline A. French, David G. Vossler, Chad Orevillo, Shikha Polega, Randall Kaye, and the LP352‐201 Study Investigators, Kore Liow, Ena Zhu, Jennifer Waldron, Hayley Groubert, Alexis Anderson, Pavel Klein, Salman Hashmi, Shicong Ye, Anita Farhi, David Vossler, Dione M. Froman, Shannon L. Hoffman‐Huffaker, Ki Hyeong Lee, AnnaLyn Dallas, Amir Arain, Laura Beeler, Michael Macken, Irena Bellinski, Elizabeth Cunningham, James Renfroe, Shezsay Colbert, Robert Hogan, Patty Schaefer, Susan Shaw, Sheetal Desai, Ahmed Sadek, Haile Robertson, Kamil Detyniecki, Anabela Cieslicki, Ruben Kuzniecky, Sarah Goodman, Selim Benbadis, Marina Azevedo, Sami Aboumatar, Julie Biel, Nilika Singhal, Emerald Wan, Evan Fertig, Hannah Hart, Debopam Samanta, Sarah Hankins, Steven Wolf, Patricia Pena, Robert Nahouraii, M. J. Mari, David Burdette, Stephanie Mueller, Karen Keough, Victoria Henderson, Talitha Durgin, Terence O’Brien, Rafael Smith, Jack Germaine, Kate Riney, Lori Anthony, David Reutens, Kimberley Irwin, Michael Fahey, Melissa Batt, Stephanie Kaladis, Kasthoori Jeyachanthiran, Ingrid Scheffer, Rebecca Wharrie, Greesha Zacharia, Brittany Walsh, Heather Robinson, Sharon Ganter +74 morewiley +1 more source[2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death].
Kardiologia polska, 2015 S. Priori, Carina Blomström-Lundqvist, Andrea Mazzanti, Nico Blom, Martin Borggrefe, John Camm, P. M. Elliott, Donna Fitzsimons, Róbert Hatala, G. Hindricks, P. Kirchhof, K. Kjeldsen, K. Kuck, A. Hernández–Madrid, Nikolaos Nikolaou, T. Norekvål, Christian Spaulding, Dirk J Van Veldhuisen +17 moresemanticscholar +1 more sourceClinical outcomes following stereotactic MRI‐guided laser ablation in children with tuberous sclerosis complex and intractable epilepsy
Epilepsia, EarlyView.Abstract Objective
In children with tuberous sclerosis complex (TSC) and drug‐resistant epilepsy (DRE), magnetic resonance imaging–guided stereotactic laser ablation (SLA) therapy offers less‐invasive treatment compared to craniotomy and resection. Our study seeks to further expand on the long‐term outcomes in patients with TSC‐related DRE who have ...Chelsey Ortman, Rohini Coorg, Irfan Ali, Dave Clarke, Gloria Diaz‐Medina, Kimberly Houck, Akshat Katyayan, Laura Masters, Deepankar Mohanty, Anuranjita Nayak, Michael Quach, Vijay M. Ravindra, James J. Riviello, Sonali Sen, Elaine Seto, Danielle Takacs, Cristina Trandafir, John T. Freiling, Karen Evankovich, Yingchao Yuan, Kalman A. Katlowitz, Daniel Curry, Howard L. Weiner, Anne Anderson +23 morewiley +1 more sourceProposed criteria of levels of evidence for co‐occurring epilepsy in people with functional/dissociative seizures
Epilepsia, EarlyView.Abstract Objective
This work was undertaken to describe the level of evidence for co‐occurring epileptic seizures in patients with known functional/dissociative seizures (FDS) using stratification criteria analogous to the International League Against Epilepsy criteria for functional seizures.Shruti N. Iyer, Zachary Duarte, Gabriela Figueiredo Pucci, Tara Pirnia, Katherine N. McFarlane, Danielle R. Carns, Alex Israel, Kyr Goyette, Brittany Concilus, Nicholas J. Beimer, Page B. Pennell, M. Angela O'Neal, Laura A. Strom, Laura A. Kirkpatrick, Joseph Ta, Carolina Cuello‐Oderiz, Wesley T. Kerr +16 morewiley +1 more sourceCardiac arrhythmia prevalence and risk factors in 24‐h electrocardiograms of sedentary horses
Equine Veterinary Journal, EarlyView.Abstract Background
Cardiac arrhythmias are common in horses, but their clinical relevance remains controversial. Objectives
To describe prevalence and identify risk factors for arrhythmias that may warrant additional screening in a sedentary mixed‐breed population of horses. Study Design
Prospective cross‐sectional.Lauren T. Maas, Elizabeth Williams Louie, Carrie J. Finno, Callum G. Donnelly, Joshua A. Stern, Ashley E. Hill, Jessica M. Morgan +6 morewiley +1 more source