Results 141 to 150 of about 4,065,133 (366)

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Restrictive or Liberal Red‐Cell Transfusion for Cardiac Surgery

New England Journal of Medicine, 2017
D. Mazer, R. Whitlock, D. Fergusson, Judith Hall, E. Belley‐Cote, K. Connolly, Boris Khanykin, A. Gregory, É. de Médicis, S. McGuinness, A. Royse, F. Carrier, P. Young, J. Villar, H. Grocott, M. Seeberger, S. Fremes, F. Lellouche, S. Syed, K. Byrne, S. Bagshaw, N. Hwang, C. Mehta, T. Painter, C. Royse, S. Verma, G. Hare, A. Cohen, K. Thorpe, P. Jüni, N. Shehata   +30 more
semanticscholar   +1 more source

The future of cardiac surgery [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2010
openaire   +3 more sources

Podocyte RIPK3 Deletion Improves Diabetic Kidney Disease by Attenuating NF‐κB p65 Driven Inflammation

Advanced Science, EarlyView.
Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li, Jiaying Li, Ruizhao Li, Xingchen Zhao, Yuanhan Chen, Yating Cai, Yan Yang, Weiteng Wang, Siqi Zheng, Li Zhang, Xinling Liang   +10 more
wiley   +1 more source

Supplementum 278: Abstracts of the joint annual meeting of the Swiss Societies of Cardiology and Cardiac Surgery

Swiss Medical Weekly
Swiss Society of Cardiology, Swiss Society of Cardiac Surgery   +1 more
doaj   +1 more source

Experimental Cardiac Surgery in the Calf

, 1967
Lawrence I. Bonchek, Constantine J. Tatooles, Nina S. Braunwald   +2 more
openalex   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Suplementum 287: Abstracts of the of the joint annual meeting of the Swiss Society of Cardiology and the Swiss Society of Cardiac Surgery (Zurich, Switzerland, June 4-6, 2025)

Swiss Medical Weekly
Swiss Society of Cardiology, Swiss Society of Cardiac Surgery   +1 more
doaj   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Amiodarone and cardiac surgery [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2007
openaire   +3 more sources