Results 151 to 160 of about 928,345 (309)

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

An Otolaryngology-Focused Risk Stratification for Postoperative Dysphagia in Pediatric Cardiac Surgery. [PDF]

Laryngoscope Investig Otolaryngol
Zhang M, Mansoor B, Frelier M, Wang C, Kou YF, Chorney SR, Johnson R.   +6 more
europepmc   +1 more source

Risk Factors for Postoperative Bleeding After Cardiac Surgery Under Cardiopulmonary Bypass [PDF]

Abderrahim Essalama, sawsan chetoui, Mohamed Khatouf, Abdelkarim Shimi, D. Ali, Brahim Bichri, Abderrahim El Bouazaoui, Samira El Fakir   +7 more
openalex   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Fast-Track Extubation After Cardiac Surgery: A Narrative Review. [PDF]

J Cardiovasc Dev Dis
Christophides A, DiMaria S, Jacob SA, Feit A, Oster J, Bergese S.   +5 more
europepmc   +1 more source

Machine Learning-Based Cardiac Output Estimation Using Photoplethysmography in Off-Pump Coronary Artery Bypass Surgery [PDF]

Cecilia A. Callejas Pastor, Chahyun Oh, Boohwi Hong, Yunseo Ku   +3 more
openalex   +1 more source

Use of tissue microdialysis to investigate hyperlactataemia following paediatric cardiac surgery [PDF]

, 2008
Riad B.M. Hosein, Kevin Morris, William J. Brawn, David J. Barron   +3 more
openalex   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Kidney Tubule Secretion and AKI After Cardiac Surgery. [PDF]

Kidney Int Rep
Gutiérrez OM, Tamhane A, Frey JA, Chu CM, Shingler L, Keister A, Bullen AL, Jaeger BC, Judd SE, Siew ED, Shlipak MG, Bonventre JV, Levitan EB, Seegmiller JC, Wang HE, Ix JH.   +15 more
europepmc   +1 more source

Successful Management of Primary Cardiac Lymphoma with Minimal Debulking Surgery Combined with Adjuvant Chemotherapy

, 2015
Tae Hee Hong, Dong Seop Jeong
openalex   +1 more source