Results 181 to 190 of about 518,643 (317)
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang+25 more
wiley +1 more source
Pleural Effusion Trajectories and Clinical Outcomes in Cardiac Surgery Patients. [PDF]
Zhong J+7 more
europepmc +1 more source
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen+8 more
wiley +1 more source
Profound Thrombocytopenia and Dyspnea 11 Days After Cardiac Surgery. [PDF]
Vuong S+3 more
europepmc +1 more source
Molecular Creep Induced Fatigue Rupture of Fibrin Clots
Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu+5 more
wiley +1 more source
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao+20 more
wiley +1 more source
Cardiac Surgery During and After the Pandemic: A Retrospective Analysis of UK Trends and Outcomes. [PDF]
Dong T+4 more
europepmc +1 more source
Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez+20 more
wiley +1 more source
Genome sequencing is critical for forecasting outcomes following congenital cardiac surgery. [PDF]
Watkins WS+25 more
europepmc +1 more source