Results 81 to 90 of about 762,849 (265)

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du   +9 more
wiley   +1 more source

Elective and primary angioplasty at hospitals without on-site surgery versus with on-site surgery: results from a national registry [PDF]

open access: yes, 2008
INTRODUCTION: Current European clinical guidelines do not restrict interventional cardiology at centers without on-site surgical backup, but disagreement still exists whether hospitals with cardiac catheterization laboratories, but without on-site ...
Baptista, J   +3 more
core  

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

open access: yesAdvanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong   +20 more
wiley   +1 more source

René Géronimo Favaloro : pioneer of Cardiac Surgery [PDF]

open access: yes, 2005
Dr. René G. Favaloro moved to the Cleveland Clinic in 1962 and proceeded to reshape the face of cardiac surgery as we knew it. Together with his colleagues at the Cleveland Clinic, Drs.
Captur, Gabriella
core  

Platelet microvesicles (microparticles) in cardiac surgery

open access: yes, 2016
SIGNIFICANT POSTOPERATIVE BLEEDING is a common risk of cardiac surgery, with approximately 3.5% of patients requiring surgical re-exploration.1 Re-exploration is associated with adverse outcomes, including infections, ischemia, and increased 30-day ...
Englyst, Nicola A.   +3 more
core   +1 more source

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li   +12 more
wiley   +1 more source

An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari   +20 more
wiley   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

Asymptomatic cardiac rhabdomyoma in neonates : is surgery indicated? [PDF]

open access: yes, 2009
Neonatal Tuberose sclerosis complex may be associated with symptomatic cardiac rhabdomyomas. Cardiac rhabdomyomas are the most common cardiac tumours.
Abdel-Aziz, Mohamed A.S.   +2 more
core  

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