Results 261 to 270 of about 896,715 (351)

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Incidence and Risk Factors of Dysphagia After Cardiac Surgery: A Scoping Review. [PDF]

J Clin Med
Kourek C, Labropoulou V, Michou E, Dimopoulos S.   +3 more
europepmc   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

The Importance of Perinatal Follow-Up in the Management of Critical Congenital Heart Diseases: A Pediatric Heart Center Experience. [PDF]

Children (Basel)
Genc HZ, Oguz D, Gumustas M, Yavuzcan Ozturk D, Kurt Bilirer K, Polat I, Cetinkaya M, Hatemi AC, Ozturk E.   +8 more
europepmc   +1 more source

Clinical Experiences with Induced Cardiac Arrest During Intracardiac Surgical Procedures*

Annals of Surgery, 1957
Charles Sergeant, Edward Green, Conrad R. Lam, Thomas Gahagan   +3 more
openaire   +4 more sources

High‐Throughput MicroED for Probing Ion Channel Dynamics

Advanced Science, EarlyView.
High‐throughput MicroED offers a new approach for visualizing ion channel dynamics. This approach reveals NaK’s sodium binding modes and NaK2CNG’s potassium‐induced selectivity filter dilation and gating. By capturing these distinct structures, this work challenges traditional models of ion channel permeation and selectivity. Abstract Ion channels play
Marc J Gallenito, Max TB Clabbers, Jieye Lin, Johan Hattne, Tamir Gonen   +4 more
wiley   +1 more source

Establishing a robotic aortic valve replacement program in Spain: growing opportunities for Europe. [PDF]

Ann Cardiothorac Surg
Sandoval E, Pereda D.
europepmc   +1 more source

A Generative AI‐Assisted Piezo‐MEMS Ultrasound Device for Plant Dehydration Monitoring

Advanced Science, EarlyView.
This study introduces a complementary metal–oxide–semiconductor (CMOS)‐compatible wearable piezoelectric micromachined ultrasound transducers (PMUTs) that sandwiches the leaf (PMUT–Leaf–PMUT, PLP) and employs generative artificial intelligence for real‐time analysis.
Kaustav Roy, Darren Sim, Luwei Wang, Zixuan Zhang, Xinge Guo, Yao Zhu, Sanjay Swarup, Chengkuo Lee   +7 more
wiley   +1 more source

Study protocol for an internahaational prospective non-randomised trial evaluating the long-term outcomes of transcatheter aortic valve implantation versus surgical aortic valve replacement for aortic-valve stenosis in patients at risk to severe valve obstruction: the TAVISAR trial. [PDF]

BMJ Open
Nappi F, Bourgois C, Nenna A, Salsano A, Schoell T, El-Dean Z, Fiore A, Spadaccio C.   +7 more
europepmc   +1 more source

Label‐Free Single‐Molecule Immunoassay

Advanced Science, EarlyView.
Label‐free single‐molecule immunoassay (LFSMiA) enables ultra‐sensitive and wide dynamic range protein detection in whole blood samples. LFSMiA features real‐time single‐molecule imaging by plasmonic scattering microscopy, background reduction by a 2‐step sandwich assay, minimizing matrix effect by dynamic tracking of single binding events, and ...
Xiaoyan Zhou, Chao Chen, Shuang Zhou, Guangzhong Ma, Mohammad Javad H. N. Chemerkouh, Christine L. H. Snozek, Eric H. Yang, Jiapei Jiang, Brandyn Braswell, Zijian Wan, Xinyu Zhou, Shaopeng Wang   +11 more
wiley   +1 more source