Results 261 to 270 of about 3,982,954 (327)

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Incidence of Infective Endocarditis in Dogs After Balloon Dilatation of Congenital Pulmonic Stenosis Without Peri- and Postoperative Antimicrobial Prophylaxis. [PDF]

Animals (Basel)
Zeedijk DI, Szatmári V.
europepmc   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Extracellular Matrix Tissue Patch for Septal Defect Repair in Pediatric Cardiac Surgery: A Single-Center Experience. [PDF]

J Clin Med
Gładki M, Bednarek PR, Węclewska A, Urbanowicz T, Olasińska-Wiśniewska A, Kociński B, Rosada-Kurasińska J, Jemielity M.   +7 more
europepmc   +1 more source

Early clinical outcomes of routine prophylactic use of a gentamicin-impregnated sponge in all consecutive patients undergoing cardiac surgical operations: a single-center experience. [PDF]

Kardiochir Torakochirurgia Pol
Witkowska A, Koziarska K, Kaczmarek J, Rodzki M, Jemielity M, Perek B.   +5 more
europepmc   +1 more source

Beyond Surgical Access: Evidence Supporting a Multidimensional Concept of Surgical Invasiveness in Contemporary Cardiac Surgery. [PDF]

J Cardiovasc Dev Dis
Poddi S, Rungatscher A.
europepmc   +1 more source

Anatomical Study of the Triangle of Brocq and Mouchet and Its Clinical Implications for Coronary Interventions in Human Cadaveric Hearts. [PDF]

Cureus
V A, Ramachandran K.
europepmc   +1 more source

Feasibility, Acceptability and Early Outcomes of Concomitant Aortic and Mitral Valve Surgery via a Single-Incision Right Anterior Minithoracotomy: A Retrospective Cohort Study. [PDF]

J Clin Med
Amanov L, Ali-Hasan-Al-Saegh S, Arjomandi Rad A, Salman J, Ius F, Rümke S, Aburahma K, Schmitto JD, Schmack B, Ruhparwar A, Zubarevich A, Weymann A.   +11 more
europepmc   +1 more source

[Pediatric cardiac surgical procedures in Poland in 2001].

Kardiologia polska, 2003
openaire   +1 more source