Results 291 to 300 of about 896,715 (351)

Complexity in aortic arch surgery and laws of diminishing return. [PDF]

J Thorac Dis
Shuhaiber J.
europepmc   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Advancing robotic aortic valve replacement beyond isolated therapy: a platform for multivalve therapy. [PDF]

Ann Cardiothorac Surg
Wei LM, Badhwar V.
europepmc   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

FDA Approval of Cardiac Valve Devices Implanted in a National Cohort of Pediatric Patients, 2016-2022.

JAMA Pediatr
Wunnava S, Miller TA, Nathan M, Bourgeois FT.   +3 more
europepmc   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Ionic Double‐Network Hydrogels for Integrated Electromagnetic Shielding and Self‐Powered Sensing in Wearable Electronics

Advanced Science, EarlyView.
A multifunctional dual network ionic hydrogel is used to address the challenges of EMI and health detection integration for CIEDs. An absorption‐based EMI shielding mechanism is achieved through ion polarization/interfacial relaxation. With an optimal SE of 63.75 dB and absorption loss greater than 93%, the wirelessly integrated self‐powered sensor in ...
Chenchen Wang, Yao Ding, Tianzhao Wu, Zihua Li, Chuanshuang Hu, Zhuoqun Wang, Yonghui Zhou, Xiuyi Lin, Weiwei Zhang, Jiangtao Xu   +9 more
wiley   +1 more source

Intrapericardial Extra-Anatomic Aorto-Aortic Bypass for Aortic Coarctation in Adults. [PDF]

Braz J Cardiovasc Surg
Soto ES, Merino GB, Larenas AS, Lagos RG, Melo RR.   +4 more
europepmc   +1 more source

Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications

Advanced Electronic Materials, EarlyView.
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster, Prashant Sankaran, Eloise Bihar   +2 more
wiley   +1 more source

Pain Management in Minimally Invasive Cardiac Surgery: A Review of Current Clinical Evidence. [PDF]

Pain Ther
Dost B, Turunc E, Aydin ME, Kaya C, Aykut A, Demir ZA, Narayanan M, De Cassai A.   +7 more
europepmc   +1 more source