Results 151 to 160 of about 433,212 (254)

Giant cardiac tumor resection combined with left ventricular reconstruction. [PDF]

J Cardiothorac Surg
Chen G, Ran H, Su C, Chen X.
europepmc   +1 more source

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

When Is Resection of a Cardiac Tumor With Metastatic Disease Acceptable? [PDF]

JACC Case Rep
Dhingra NK, Alhothali AM, Nyamande D, Ghunaim AH, Cusimano RJ.   +4 more
europepmc   +1 more source

Metastatic patterns and prognosis of patients with primary malignant cardiac tumor. [PDF]

Front Cardiovasc Med, 2022
Guan T, Wei Q, Tang Y, Zhao H, Lu Z, Feng W, Teng Y, Luo Z, Chi K, Ou C, Chen M.   +10 more
europepmc   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Cardiac Tumor Within the Left Ventricle: Thrombus or Something Else? [PDF]

JACC Case Rep
Barron KT, Landrum A, Abu Daya H, Clarkson S.   +3 more
europepmc   +1 more source

Diagnostic dilemma in a case of neonatal cardiac tumor - The importance of histopathology and mutation analysis in clinical practice. [PDF]

Ann Pediatr Cardiol, 2023
Sardar S, Dey R, Mukherjee S, Pal S.
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Atypical Primary Cardiac Tumor Engulfing Papillary Muscle of the Tricuspid Valve. [PDF]

JACC Case Rep
Zeineddine RM, Farina JM, Arsanjani R, Sell-Dottin K.   +3 more
europepmc   +1 more source

A rare case of cardiac tumor of the interventricular septum complicated with atrioventricular block. [PDF]

J Cardiol Cases, 2022
Komoriya Y, Suzuki S, Iwakawa N, Kondo T, Murohara T.   +4 more
europepmc   +1 more source