Results 191 to 200 of about 4,596,241 (334)

Diagnostic dilemma in a case of neonatal cardiac tumor - The importance of histopathology and mutation analysis in clinical practice. [PDF]

Ann Pediatr Cardiol, 2023
Sardar S, Dey R, Mukherjee S, Pal S.
europepmc   +1 more source

Cardiac tumors: imaging findings, clinical correlations and surgical treatment in a 15 years single-center experience

, 2022
Paola Gripari, Mauro Pepi, Laura Fusini, Gloria Tamborini, Maria Elisabetta Mancini, Daniele Andreini, Gianluca Pontone, Matteo Saccocci, Ilaria Giambuzzi, Francesco Alamanni, Marco Zanobini   +10 more
openalex   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Metastatic cardiac tumor resulting in cardiogenic shock from muscle-invasive urothelial carcinoma of the bladder: a case report. [PDF]

Urol Case Rep
Wesemann L, Thomas B, Kim D, Taylor Z, McCoo M, McMahon GC.   +5 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Anesthetic management of primary cardiac tumor in the coronary sinus and right atrium. [PDF]

Saudi J Anaesth, 2022
Yamada A, Miyawaki I, Mima H.
europepmc   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Electrical alternans of the Q-T interval and fatal arrhythmias caused by neonatal cardiac tumor: a case report. [PDF]

Front Cardiovasc Med
Wang G, Ding J, Wu H, Chen Y, Deng X, Li H, Li H.   +6 more
europepmc   +1 more source

Three-dimensional transesophageal echocardiography guided endomyocardial biopsy in diagnosis of cardiac tumor. [PDF]

Cardiol J, 2022
Ozierański K, Szczerba E, Tymińska A, Marchel M, Piątkowski R, Wojnicz R, Jaguszewski M, Grabowski M.   +7 more
europepmc   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source