Racial disparities in treatment patterns and clinical outcomes in patients with HER2-positive metastatic breast cancer. [PDF]
Data characterizing demographics, treatment patterns, and clinical outcomes in black patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) are limited.
Abidoye, Oyewale O+8 more
core +1 more source
SynergyNet: Bridging the Gap between Discrete and Continuous Representations for Precise Medical Image Segmentation [PDF]
In recent years, continuous latent space (CLS) and discrete latent space (DLS) deep learning models have been proposed for medical image analysis for improved performance. However, these models encounter distinct challenges. CLS models capture intricate details but often lack interpretability in terms of structural representation and robustness due to ...
arxiv
Safety and pharmacokinetics of MM-302, a HER2-targeted antibody–liposomal doxorubicin conjugate, in patients with advanced HER2-positive breast cancer: A phase 1 dose-escalation study [PDF]
BackgroundThis phase 1 dose-escalation trial studied MM-302, a novel HER2-targeted PEGylated antibody-liposomal doxorubicin conjugate, in HER2-positive locally advanced/metastatic breast cancer.MethodsPatients were enrolled in four cohorts: MM-302 ...
Adiwijaya, Bambang S+14 more
core +2 more sources
Building medical image classifiers with very limited data using segmentation networks [PDF]
Deep learning has shown promising results in medical image analysis, however, the lack of very large annotated datasets confines its full potential. Although transfer learning with ImageNet pre-trained classification models can alleviate the problem, constrained image sizes and model complexities can lead to unnecessary increase in computational cost ...
arxiv +1 more source
The characteristics of invasive cardiac lipoma: case report and literature review
Invasive cardiac lipoma is a rare type of primary cardiac tumor that is composed of adipose tissue but infiltrating the adjacent structures. It is a benign tumor that can cause significant morbidity and mortality due to its size and location within the ...
Xiliang Zhu+5 more
doaj +1 more source
Unsupervised Multi-Modality Registration Network based on Spatially Encoded Gradient Information [PDF]
Multi-modality medical images can provide relevant or complementary information for a target (organ, tumor or tissue). Registering multi-modality images to a common space can fuse these comprehensive information, and bring convenience for clinical application.
arxiv
Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S+6 more
core +1 more source
Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases.
Importance Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be documented in various tissues, but the frequency of cardiac involvement as well as possible consequences are unknown. Objective To evaluate the presence of SARS-CoV-2 in the
D. Lindner+12 more
semanticscholar +1 more source
Chemotherapeutic agents have been linked to immunogenic cell death (ICD) induction that is capable of augmenting anti-tumor immune surveillance. The cardiac glycoside oleandrin, which inhibits Na+/K+-ATPase pump (NKP), has been shown to suppress breast ...
Xiaoxi Li+5 more
semanticscholar +1 more source
Multimodality imaging assessment of primary pericardial rhabdomyosarcoma: a case report
Primary pericardial sarcomas are rare and lethal diseases. To date, only a few cases of primary pericardial sarcomas, such as rhabdomyosarcoma (RMS), have been reported.
Xingxuan Li+7 more
doaj +1 more source